Search for dissertations about: "M. Thomas"

Showing result 16 - 20 of 85 swedish dissertations containing the words M. Thomas.

  1. 16. Structural investigation of SOD1 aggregates in ALS : identification of prion strains using anti-peptide antibodies

    Author : Johan Bergh; Thomas Brännström; Stefan L. Marklund; Peter M. Andersen; Joakim Bergström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; SOD1; prion; motor neuron disease; neurodegeneration; strain; seeding; protein aggregation; transgenic mice; peptide antibodies; Neurology; neurologi;

    Abstract : Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative syndrome characterized by progressive degeneration of motor neurons that result in muscle wasting. The symptoms advance gradually to paralysis and eventually death. Most patients suffer from sporadic ALS (sALS) but 10% report a familial predisposition. READ MORE

  2. 17. Sequential Monte Carlo for inference in nonlinear state space models

    Author : Johan Dahlin; Thomas Schön; Fredrik Lindsten; Adam M. Johansen; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Abstract : Nonlinear state space models (SSMs) are a useful class of models to describe many different kinds of systems. Some examples of its applications are to model; the volatility in financial markets, the number of infected persons during an influenza epidemic and the annual number of major earthquakes around the world. READ MORE

  3. 18. Long QT syndrome : studies of diagnostic methods

    Author : Ulla-Britt Diamant; Steen M Jensen; Annika Rydberg; Thomas Gilljam; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; kardiologi; Cardiology;

    Abstract : Background: The Long QT Syndrome (LQTS) is a hereditary heart disease with risk of malignant ventricular arrhythmia and sudden cardiac death. Despite our increased knowledge about genotype and phenotype correlation we still rely on the 12-lead ECG for assessment of the QT interval and the T-wave morphology for diagnosis and risk stratification. READ MORE

  4. 19. SOD1 prions transmit templated aggregation and fatal ALS-like disease

    Author : Elaheh Ekhtiari Bidhendi; Thomas Brännström; Stefan L. Marklund; Peter M. Andersen; Inger Nennesmo; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ALS; amyotrophic lateral sclerosis; SOD1; prion; neurodegeneration; strain; seeding; protein misfolding; protein aggregation; propagation; transgenic mice; Pathology; patologi; Neurology; neurologi;

    Abstract : Amyotrophic lateral sclerosis (ALS) is an adult-onset fatal neurodegenerative disease characterized by a progressive degeneration of the upper and lower motor neurons. The resulting paresis begins focally, usually in one muscle, and spreads contiguously, leading to muscle wasting, progressive paralysis and eventually death. READ MORE

  5. 20. Shaping urban environments through human selection for plant traits

    Author : Julie Goodness; Erik Andersson; Thomas Elmqvist; Pippin M. L. Anderson; Sarel Cilliers; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; Cape Town; cities; ecosystem services; environmental management; functional traits; interdisciplinary; landscaping preferences; residential landscapes; social-ecological system; Stockholm; traits; urban ecology; Kapstaden; städer; kulturella ekosystemtjänster; ekosystemtjänster; miljöförvaltning; funktionella egenskaper; tvärvetenskaplig; anläggningspreferenser; bostadsmiljö; socialekologiska system; Stockholm; växtegenskaper; urban ekologi; Sustainability Science; vetenskap om hållbar utveckling;

    Abstract : Cities, as home to the majority of the world’s people, are significant sites for addressing challenges of achieving sustainability and securing human wellbeing. Urban environments are complex social-ecological systems, and meeting these challenges requires better understandings of the interactions of social and ecological elements. READ MORE