Search for dissertations about: "M1 protein"

Showing result 1 - 5 of 58 swedish dissertations containing the words M1 protein.

2. 1. Bacterial virulence or exorbitant host response? On innate immunity against the streptococcal M1 protein

   Author : Sandra Persson; Infektionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Skin infection; Streptococcus pyogenes; M1 protein; Innate Immunity; Host response; Virulence factor; Neutrophil recruitment; Heparin-binding protein HBP ; Leptospirosis;

   Abstract : Bacterial infection is inevitable throughout a lifetime. What differs between mild andserious infections is the pathogen responsible and how the host immune systemresponds to it. A fundamental role to prevent infection is a proper physical barrier such as the skin and mucosa. READ MORE

4. 2. Immunoglobulin-binding bacterial surface proteins; biomedical tools and virulence factors

   Author : Britt-Marie Kihlberg; Infektionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Phagocytosis; M-like protein; M protein; Protein L; Protein G; Ig-binding; Streptococcus pyogenes; Fc Receptors; mykologi; virologi; bakteriologi; Mikrobiologi; mycology; virology; bacteriology; Microbiology; Cysteine proteinase; Streptolysin;

   Abstract : Many bacteria express immunoglobulin(Ig)-binding proteins that interact with Ig in a non-immune manner. Several of these Ig-binding bacterial proteins have been well characterized and are widely used as reagents for analysis and purification of Ig's. READ MORE

5. 3. Evolutionary Analysis and Posttranslational Chemical Modifications in Protein Redesign : A Study on Mu Class Glutathione Transferases

   Author : Ylva Ivarsson; Bengt Mannervik; Gun Stenberg; Richard N. Armstrong; Uppsala universitet; []
   Keywords : Biochemistry; glutathione transferase; evolutionary analysis; positive selection; epoxide; stereoselectivity; protein modification; Biokemi;

   Abstract : Glutathione transferases (GSTs) constitute a family of multifarious enzymes that conjugate glutathione (GSH) with a wide range of electrophiles. GSTs are grouped into different classes based on protein sequence similarities. Despite high sequence identities between GSTs of the same class they often display different substrate specificites. READ MORE

6. 4. Actions of Antimicrobial Peptides and Bacterial Components in Inflammation

   Author : Thorgerdur Sigurdardottir; Anestesiologi och intensivvård; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; LL-37; M1 protein; S. pyogenes; Toll-like receptors; phenylephrine; nitr1c oxide; antimicrobial peptides;

   Abstract : Antimicrobial peptides are evolutionally ancient parts of the innate immune system and their primary role is to protect us from infections. The human cathelicidin-derived antimicrobial peptide, LL-37, not only possesses broad spectrum antimicrobial activities but is also able to bind and neutralize bacterial lipopolysaccharide (LPS), an important trigger of the widespread inflammatory response contributing to septic shock. READ MORE

7. 5. Analysis of the molecular interplay between Streptococcus pyogenes and its human host

   Author : Björn Johansson; Infektionsmedicin; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; bacteriology; virology; mycology; Biomedicinska vetenskaper allmänt ; Regulation; General biomedical sciences; IdeS; Enzyme; Virulence factors; Virulence; Bacteria; Streptococci; bakteriologi; virologi; mykologi; GAS; Protein; Mikrobiologi;

   Abstract : The common human pathogen Streptococcus pyogenes is the causative agent of numerous mild and severe clinical conditions. It expresses a number of secreted or cell wall-anchored proteins that modulate the human immune system and facilitate colonization and spread of the pathogen in the human host. During S. READ MORE