Search for dissertations about: "M2 macrophage"

Showing result 1 - 5 of 32 swedish dissertations containing the words M2 macrophage.

  2. 1. Functional properties of galectin-3. Beyond the sugar binding

    Author : Adriana Lepur; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; galectin-3; galectin-1; M1 macrophage; M2 macrophage; self-association; fluorescence anisotropy; citrus pectin; galactomannane;

    Abstract : Contemporary diseases like diabetes, asthma, atherosclerosis etc. are marked by chronic inflammation, often supported by the activity of different macrophages. Proteins from galectin family were found to contribute to disease pathophysiology. Therefore, there is an intensive interest in understanding different galectin functions. READ MORE

  4. 2. Cancer and Inflammation : Role of Macrophages and Monocytes

    Author : Alexander Hedbrant; Jonny Wijkander; Dick Delbro; Ann Erlandsson; Anita Sjölander; Karlstads universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; M1 macrophages; M2 macrophages; colon cancer; lung cancer; prostaglandin E2; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Macrophages are cells of the innate immune system that can be found in large quantities in cancer tumors and affect cancer progression by regulating growth and invasiveness of cancer cells. There are two main phenotypes of macrophages denoted M1 and M2. READ MORE

  5. 3. The role of the DAMP molecule HMGB1 in neuroinflammation and macrophage activation

    Author : Henna Salo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : High mobility group box 1 (HMGB1) is a highly conserved nuclear protein expressed in all eukaryotic cells. While its nuclear functions are vital, we know today that HMGB1 also functions as a Damage Associated Molecular Pattern (DAMP). READ MORE

  6. 4. Lyso-PC and macrophage interplay. Scavenging through the fatty side of atherosclerosis

    Author : Katarina Berg; Kardiovaskulär forskning - immunitet och ateroskleros; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Atherosclerosis is triggered by LDL entrapment in the vessel wall. Oxidation and enzymatic processing of LDL give rise to inflammatory mediators such as lyso-PC. These inflammatory mediators attract monocytes into the vessel wall where they differentiate into macrophages. The macrophages adopt different phenotypes depending on the environment. READ MORE

  7. 5. Crosstalk between colorectal cancer cells and tumour-associated macrophages

    Author : Yuan Zhang; Malmö Cellpatologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD47; tumour-associated macrophage; matrix metalloproteinase; cell migration; colon cancer;

    Abstract : Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of death from cancer worldwide. People suffering from inflammatory bowel disease, such as Crohns’ disease and ulcerative colitis, are at an increased risk of developing CRC. The development of CRC is highly influenced by the tumour microenvironment. READ MORE