Search for dissertations about: "MAIT cells"

Showing result 1 - 5 of 21 swedish dissertations containing the words MAIT cells.

  2. 1. Unconventional T cells in colon adenocarcinomas

    Author : William Rodin; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Unconventional T cells; MAIT cells; γδ T cells; Colorectal cancer; Tumour immunity;

    Abstract : Many factors influence the initiation and growth of tumours. The infiltration and activity of immune cells in the tumour microenvironment are widely recognised as key factors affecting the clinical outcome of cancer. READ MORE

  4. 2. Bacterial Regulation of Peripheral Immunity : Mechanistic insights from lactobacilli and Staphylococcus aureus

    Author : Manuel Mata Forsberg; Eva Sverremark-Ekström; Monika Brunner-Weinzierl; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Immune regulation; Cytokines; T cells; gamma-delta T cells; MAIT cells; NK cells; Lactobacillus; Staphylococcus aureus; staphylococcal enterotoxins; molekylär biovetenskap; Molecular Bioscience;

    Abstract : There is a constant cross-talk between our immune system and the colonizing microbiota. The gut resident bacteria produce a broad range of molecules with regulatory activities in both local and distal tissues. Staphylococcus (S. READ MORE

  5. 3. Regulatory T cells and mucosal-associated invariant T cells in colon adenocarcinomas; Phenotype and function

    Author : Filip Ahlmanner; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colon cancer; regulatory T cells; CD39; adenosine; immune checkpoint molecules; immunosuppression; MAIT cells; cytokines; cancer-specific survival;

    Abstract : In many solid cancers, and also in colon adenocarcinomas, an increased accumulation of lymphocytes is beneficial for the patient. However, tumor-infiltrating immune cells may be either pro- or anti-tumorigenic and the balance between these two counteracting forces partly determines patient outcome. READ MORE

  6. 4. The antimicrobial role of human MAIT cells

    Author : Caroline Boulouis; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : MAIT cells are unconventional T cells that have characteristics of both innate and adaptive immunity. Their fast mobilization and wide distribution in tissues make them part of the first line of defense against infection. MAIT cells recognize riboflavin-related metabolites produced by bacteria and presented by MR1. READ MORE

  7. 5. Role of MAIT cells in human antimicrobial immunity

    Author : Joana Dias; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Mucosa-associated invariant T (MAIT) cells are a relatively recently discovered subset of unconventional T cells. In humans, MAIT cells are predominantly CD8+CD4- (CD8+) with a smaller CD8-CD4- (double-negative, DN) subset, and they are abundant in the peripheral blood, liver, and mucosal tissues. READ MORE