Search for dissertations about: "MAIT cells"

Showing result 11 - 15 of 21 swedish dissertations containing the words MAIT cells.

  2. 11. Innate-like T cells in the immunopathogenesis of HIV-1 infection

    Author : Kerri Guth Lal; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : The immunodynamics of HIV infection have been studied for over three decades in the hopes of determining underlying mechanisms that contribute to the sustained immune dysfunction observed even in individuals on therapy. Conventional and adaptive T cells are both the target of the virus and considered the main players in controlling viral burden. READ MORE

  4. 12. In situ characterization of immune cells mediating potential control of HIV infection in the female genital mucosa

    Author : Anna Gibbs; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Heterosexual HIV transmission is the most common viral transmission route, worldwide, where young women are more susceptible to HIV infection than men. To establish a persistent infection the virus needs to cross the mucosal surface of the female genital tract (FGT). READ MORE

  5. 13. Human innate lymphocytes in host defense, tissue function and reproduction

    Author : Benedikt Strunz; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : The immune system is present in all tissues of the human body. In order to respond appropriately to infections, cells of the innate and adaptive immune system work in concert. READ MORE

  6. 14. Innate lymphocyte responses in inflammatory diseases

    Author : Johanna Emgård; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : The immune system is a highly sophisticated system that has evolved to protect the host from external and internal threats. However, under some circumstances the immune response can get dysregulated and cause inflammatory diseases. READ MORE

  7. 15. Invariant T cell subsets in immune defense of oral mucosa and skin

    Author : Michał J Sobkowiak; Karolinska Institutet; Karolinska Institutet; []
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    Abstract : Innate-like T lymphocytes such as mucosa-associated invariant T (MAIT) cells and invariant natural killer T (iNKT) cells recognize antigens presented by MR1 and CD1d molecules, respectively. As MR1 presents microbial riboflavin metabolite antigens, and CD1d presents endogenous or microbial glycolipid antigens, MAIT cells and iNKT cells survey the non-protein fraction of the potential antigenic universe. READ MORE