Search for dissertations about: "MAP kinases"
Showing result 16 - 20 of 40 swedish dissertations containing the words MAP kinases.
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16. Mechanisms of stretch-induced growth and contractile differentiation in vascular smooth muscle
Abstract : Vascular smooth muscle can adapt to increased intraluminal pressure by remodelling and hypertrophy, as seen in hypertension. The molecular mechanisms responsible for this are still incompletely characterized. READ MORE
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17. Molecular Pharmacology and Structure Function Modelling of the Leukotriene B4 Receptor BLT1
Abstract : Leukotrienes are membrane derived bioactive lipids that play an important role in immune responses by initiating and maintaining the inflammatory responses. Leukotriene B4 (LTB4) released at the site of an inflammatory response attracts, activates and prolongs the life of leukocytes and lymphocytes. READ MORE
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18. TNFalpha expression in monocytes/macrophages
Abstract : The recognition of microbes or microbial products by leukocytes is a key event in innate immunity. Binding of microbial products to cell surface receptors on phagocytes induce a response that includes the production of inflammatory mediators. One such mediator is the cytokine tumour necrosis factor alpha (TNF). READ MORE
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19. The role of PKC in neuronal differentiation and in regulation of the actin cytoskeleton during neurite outgrowth
Abstract : Protein kinase C (PKC) is a family of serine/threonine kinases subgrouped into classical (α, βI, βII, γ), novel (δ, ε, η, θ) and atypical (ζ, ι/λ) isoforms. PKC can be activated by phorbol esters, and prolonged treatment of neuroblastoma cells has been shown to induce neuronal differentiation with neurite outgrowth and increased expression of neuronal genes. READ MORE
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20. Mechanisms of insulin signaling and the role of caveolae
Abstract : Insulin regulates metabolic as well as mitogenic processes in target cells, involving a large number of mediators of signal transduction. In its role as a growth factor, insulin stimulates cell growth, in a process we demonstrate requires the participation of the Raf-1 kinase. READ MORE