Search for dissertations about: "MAP2"

Showing result 1 - 5 of 6 swedish dissertations containing the word MAP2.

2. 1. Mechanisms of traumatic brain injury in the rat : Morphological consequences and neurotrophic responses

   Author : Anders Lewén; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Cortical contusion injury; TBI; neurons; axons; dendrites; APP; MAP2; BMPR-II; ActR-I; trkB; c-fos; BDNF; PACAP; TUNEL; TGFs; serine threonine; bone morphogenetic protein; neuropeptides; reactive oxygen species; ROS; apoptosis; Neurovetenskap; Neurology; Neurologi; Neurosurgery; neurokirurgi;

   Abstract : Traumatic brain injury is a major cause of death and disability in the Western world. especially in young people. Understanding the pathophysiology of traumatic brain injury is the basis for further development of better therapeutic strategies for such patients. READ MORE

4. 2. Diagnostic and therapeutic strategies following spinal cord and brachial plexus injuries

   Author : Amar Karalija; Mikael Wiberg; Zhongyu John Li; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Spinal cord injury; brachial plexus injury; acetyl-L-carnitine; N-acetyl-cysteine; MRI; motoneurons; anatomi; Human Anatomy;

   Abstract : Traumatic injuries to the spinal cord and brachial plexus induce a significant inflammatory response in the nervous tissue with progressive degeneration of neurons and glial cells, and cause considerable physical and mental suffering in affected patients. This thesis investigates the effects of the antioxidants N-acetyl-cysteine (NAC) and acetyl-L- carnitine (ALC) on the survival of motoneurons in the brainstem and spinal cord, the expression of pro-apoptotic and pro-inflammatory cell markers, axonal sprouting and glial cell reactions after spinal hemisection in adult rats. READ MORE

5. 3. Development and Implementations of Virtual Reality for Urban Planning and Building Design

   Author : Mattias Roupé; Chalmers tekniska högskola; []
   Keywords : SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Building Information Model; Usability; Urban planning; 3D-City models; Virtual Reality; Building design;

   Abstract : The use of Virtual Reality (VR) has been seen by many as holding great potential in increasing the effectiveness and improving communication in the decision making process in urban planning and building design. VR can faulitate processes so that participants can better understand, identify and analyze problems together to improve their decision making and the future urban environment. READ MORE

6. 4. On neonatal asphyxia : clinical and animal studies including development of a simple, safe method for therapeutic hypothermia with global applicability

   Author : Linus Olson; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Recent randomized clinical trials show that hypothermia can decrease brain dysfunction in newborn infants at risk for hypoxic-ischemic encephalopathy. One goal of the present study was to develop an alternative to current relatively complex and expensive cooling methods dependent on electricity and continuous water supply. READ MORE

7. 5. On VEGF and related factors in neurotrauma

   Author : Mattias Sköld; Karolinska Institutet; Karolinska Institutet; []
   Keywords : Spinal cord; brain; motoneuron; VEGF; VEGFR1; VEGFR2; Np1; Np2; Sema3A; HIF1alpha;

   Abstract : At present, there is no cure for traumatic spinal cord and brain injuries. Therapies in use have only modest effect on outcome. Therefore, the need to better understand the biology of traumatic CNS injuries, making development of new therapies possible, is huge. READ MORE