Search for dissertations about: "MARKERS"

Showing result 16 - 20 of 2679 swedish dissertations containing the word MARKERS.

  2. 16. Molecular Markers and Hypoxia in Renal Cell Carcinoma

    Author : Roger de Alwis; Avdelningen för translationell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney cancer; CTC; RCC; Hypoxia; SEMA5B; Prognostic markers;

    Abstract : Renal cell carcinomas (RCCs) are a group of tumours that arise from the nephron within the kidney. They are characterised by an indolent growth pattern and do not display overt clinical symptoms in patients with early to locally advanced tumours. READ MORE

  4. 17. Developmental Neurotoxicity of Environmental Pollutants : Effects on neuronal protein markers after neonatal exposure

    Author : Iwa Lee; Henrik Viberg; Elena Jazin; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental neurotoxicity; Neonatal exposure; Protein markers; Environmental pollutants; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Abstract : This thesis focused on investigations of the developmental neurotoxic effects of bisphenol A (BPA) or perfluorohexane sulfonate (PFHxS), after a single neonatal exposure, during a critical period of the brain development in mice.BPA is a well-known industrial chemical used in the production of polymer products and PFHxS is used as an industrial additive as a surfactant. READ MORE

  5. 18. Epidemiology of venous thromboembolism with focus on risk markers

    Author : Magdalena Johansson; Lars Johansson; Marcus Lind; Jan-Håkan Jansson; Gerd Lärfars; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thromboembolism; venous thrombosis; deep vein thrombosis; pulmonary embolism; incidence; risk markers; diabetes; glucose; alcohol consumption; alcohol dependence; physical activity; medicin; Medicine;

    Abstract : Background: Venous thromboembolism (VTE) is a vascular disease with an incidence of approximately 140 cases per 100,000 person-years in adults. The incidence of VTE has increased over the last decades, and more than 20% of affected individuals die in the first year after diagnosis. READ MORE

  6. 19. Prognostic markers and DNA methylation profiling in lymphoid malignancies

    Author : Sujata Bhoi; Richard Rosenquist Brandell; H Denis Alexander; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lymphoid malignancies; CLL; MCL; prognostic markers; micro-RNA; methylation; stereotyped subsets;

    Abstract : In recent years, great progress has been achieved towards identifying novel biomarkers in lymphoid malignancies, including chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL), at the genomic, transcriptomic and epigenomic level for accurate risk-stratification and prediction of treatment response. In paper I, we validated the prognostic relevance of a recently proposed RNA-based marker in CLL, UGT2B17, and analyzed its expression levels in 253 early-stage patients. READ MORE

  7. 20. Characterization and Use of a Multiplex PCR-based System: Random amplified Polymorphic DNA

    Author : Christer Halldén; Malmö Klinisk kemi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; DNA mixtures; competition; graphical genotypes; bulked segregant analysis; linkage map; genetic distance; RFLP markers; RAPD markers; oilseed rape; sugar beet; Genetics; cytogenetics; Genetik; cytogenetik;

    Abstract : Random amplified polymorhic DNA (RAPD) is a PCR-based marker system that makes use of universal sets of short oligonucleotides that amplify random DNA fragments under low-stringency conditions. The RAPD marker system has found widespread use and possesses a number of very positive features, being a multiplex and universal system. READ MORE