Search for dissertations about: "MASS-SPECTROMETER"

Showing result 6 - 10 of 77 swedish dissertations containing the word MASS-SPECTROMETER.

  2. 6. Synthesis of complex organics via molecular growth mechanisms : Combined experimental and theoretical studies on ion-neutral reactions of C2H2N+ with ubiquitous hydrocarbons in Titan's ionosphere

    Author : Pantea Fathi; Wolf Geppert; Paul Scheier; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Astrochemistry; Complex molecules; Ion-neutral reactions; Mass spectrometry; Planetary and satellite atmospheres; Titan; kemisk fysik; Chemical Physics;

    Abstract : To provide insights on the molecular growth mechanisms leading to large carbon and nitrogen-bearing species in Titan’s ionosphere, laboratory measurements of ion-neutral reactions were conducted and the results are presented in the following doctoral dissertation. The product ions of the C2H2N+ reactions with saturated and unsaturated neutral hydrocarbons have been investigated using Guided Ion Beam Mass Spectrometer (GIB-MS). READ MORE

  4. 7. Interactions of chiral ions and molecules in gas phase : Towards an understanding of chiral recognition mechanism

    Author : Oleksii Rebrov; Mats Larsson; Richard Thomas; Vitali Zhaunerchyk; Anne Zehnacker-Rentien; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fysik; Physics;

    Abstract : This thesis comprises the research related to interactions of enantiopure amino acids with chiral and achiral molecules in gas phase. The investigation of the mechanism responsible for chiral discrimination is of the special interest in this work. READ MORE

  5. 8. Method and technique development in peptide and protein mass Spectrometry

    Author : Kristina Håkansson; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Materials science; electrospray ionization; peptide sequencing; Fourier transform ion cyclotron resonance; hydrogen deuterium exchange; protein structure; Materialvetenskap; Materials science; Teknisk materialvetenskap; Molecular Biotechnology; Molekylär bioteknik;

    Abstract : Mechanistic studies and applicability of several methods and techniques for studying peptides and proteins with mass spectrometry are presented. A model for the protein molecular ion formation in explosive matrix-assisted plasma desorption mass spectrometry is proposed, involving a contribution from the chemical energy release during conversion of the explosive, an enhanced protonation through collisions with products from the explosive decay, and electron scavenging by other products. READ MORE

  6. 9. Analysis of drugs and proteins in biological matrices, using different types of sample preparations and mass spectrometry

    Author : Aljona Saleh; Ingrid Granelli; Jonas Bergquist; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Bioanalysis; drugs; proteins; liquid chromatography; two-dimensional liquid chromatography; mass spectrometry; Analytical Chemistry; analytisk kemi;

    Abstract : This thesis describes bioanalysis of small and large molecules in biological matrices and includes screening of illegal drugs in urine with high resolution mass spectrometer, bioanalysis of MTH1 inhibitors in mice plasma and quantification of proteins in plasma and cell lysates.Screening of illegal drugs was based on high resolving power mass spectrometer (QTOF) and the results were compared to immunoassays. READ MORE

  7. 10. Detection and Structure Elucidation of Drug Metabolites in Biological Samples using HPLC-MS/MS Techniques

    Author : Annica Tevell Åberg; Mikael Hedeland; Ulf Bondesson; Mario Thevis; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical chemistry; Farmaceutisk kemi; analytisk farmaceutisk kemi; Analytical Pharmaceutical Chemistry;

    Abstract : This thesis describes the structure elucidation of drug metabolites in biological samples by the use of high performance liquid chromatography (HPLC) atmospheric pressure ionization (API) tandem mass spectrometry (MS/MS). Due to their different advantages, various mass analyzers have been used in the different experiments. READ MORE