Search for dissertations about: "MDMA"

Found 4 swedish dissertations containing the word MDMA.

  1. 1. In vitro cellular models for neurotoxicity studies : neurons derived from P19 cells

    Author : Dina Popova; Jacobsson Stig O.P.; Anna Forsby; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurotoxicity; Neuronal cell culture; P19 cells; SH-SY5Y cells; βIII-tubulin; Methylmercury; Okadaic acid; Acrylamide; MDMA; Piperazine-derived designer drugs.;

    Abstract : Humans are exposed to a variety of chemicals including environmental pollutants, cosmetics, food preservatives and drugs. Some of these substances might be harmful to the human body. READ MORE

  2. 2. GPCRs regulating catecholaminergic cell survival and function : focus on GPR37

    Author : Ebba Gregorsson Lundius; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Dysfunction and dysregulation of catecholaminergic signaling are major causes of many neurological and psychiatric disorders, including Parkinson’s disease (PD), schizophrenia, ADHD and drug addiction. Currently an incomplete understanding of the mechanisms regulating the function and survival of catecholaminergic neurons hinders the development of effective treatments. READ MORE

  3. 3. Mass spectrometry in the search for new drugs of abuse : method development and clinical application

    Author : Helena Nordgren; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Clinical drug testing using immunochemical screening methodology is limited regarding which analytes are covered. In this thesis, liquid chromatography was investigated as an alternative to immunochemical screening. READ MORE

  4. 4. PET studies on the mechanisms of action of antidepressant and antipsychotic drugs

    Author : Kai-Chun Yang; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Positron emission tomography (PET) is a non-invasive molecular imaging technique suitable for examination of neurochemical biomarkers in the living brain. Among these applications, PET studies are used to facilitate the development of novel psychotropic drugs. READ MORE