Search for dissertations about: "MEDICIN Kemi Biokemi"

Showing result 1 - 5 of 151 swedish dissertations containing the words MEDICIN Kemi Biokemi.

  1. 1. On the Versatility of Microwave-Assisted Chemistry Exemplified by Applications in Medicinal Chemistry, Heterocyclic Chemistry and Biochemistry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Kristina M. Orrling; Mats Larhed; Fredrik Almqvist; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; microwave-assisted chemistry; malaria; aspartic protease; plasmepsin; PfPM4; PmPM4; PoPM4; PvPM4; inhibitor; unsaturated lactone; unsaturated lactam; unsaturated amide; lactam; Bestmann s ylide; ionic liquid; polymerase chain reaction; thermophilic enzyme; NATURAL SCIENCES Chemistry Organic chemistry Pharmaceutical chemistry; NATURVETENSKAP Kemi Organisk kemi Läkemedelskemi; NATURAL SCIENCES Chemistry Organic chemistry Organic synthesis; NATURVETENSKAP Kemi Organisk kemi Organisk syntes; NATURAL SCIENCES Chemistry Biochemistry; NATURVETENSKAP Kemi Biokemi; Biochemistry; biokemi;

    Abstract : Today, the demand for speed in drug discovery is constantly increasing, particularly in the iterative processes of hit validation and expansion and lead optimization. Irradiation with microwaves (MWs) has been applied in the area of organic synthesis to accelerate chemical reactions and to facilitate the generation of new chemical entities since 1986. READ MORE

  2. 2. NMR studies of protein dynamics and structure

    University dissertation from Umeå : Umeå universitet. Kemiska institutionen

    Author : Jörgen Ådén; Magnus Wolf-Watz; Michael Sattler; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NMR; protein dynamics; relaxation; protein folding; MEDICINE Chemistry Biochemistry; MEDICIN Kemi Biokemi; NATURAL SCIENCES Chemistry Physical chemistry Biophysical chemistry; NATURVETENSKAP Kemi Fysikalisk kemi Biofysikalisk kemi; biokemi; Biochemistry; fysikalisk kemi; Physical Chemistry;

    Abstract : Enzymes are extraordinary molecules that can accelerate chemical reactions by several orders of magnitude. With recent advancements in structural biology together with classical enzymology the mechanism of many enzymes has become understood at the molecular level. READ MORE

  3. 3. Fucoidan-Mimetic Glycopolymers Synthesis and Biomedical Applications

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Mattias Tengdelius; Peter Konradsson; May Griffith; Peter Påhlsson; Mats Johansson; [2016]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The marine polysaccharide fucoidan has demonstrated several interesting biological properties, for instance being antiviral, anticoagulant, anti-inflammatory, anticancer, and platelet activating. Many of these properties are desirable for various biomedical applications. Yet, there are few reports on fucoidan being used in such applications. READ MORE

  4. 4. Unveiling Mechanistic Details of Macromolecular Interactions: Structural Design and Molecular Modelling of DNA-Protein Systems in Their Active State

    University dissertation from Linköping : Linköping University Electronic Press

    Author : Anna Reymer; [2012]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; molecular modelling; intercalation; homologous recombination; DNA; ruthenium II polypyridyl compounds; human Rad51;

    Abstract : Molecular structure is fundamental for understanding mechanisms of molecular interactions. This applies not least to understanding biological function: every biological cell, whether bacterial or human, is an immensely complex system of thousands of molecules that exist in constant motion and interaction with each other. READ MORE

  5. 5. Extracellular Matrix Based Materials for Tissue Engineering

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Cecilia Aulin; Jöns Hilborn; Tim Bowden; Laura Creemers; [2010]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Extracellular matrix; collagen synthesis; bioreactor; cell culture; bone morphogenetic protein-2; noggin; hyaluronan; cartilage; MEDICINE Physiology and pharmacology Physiology Medical technology; MEDICIN Fysiologi och farmakologi Fysiologi Medicinsk teknik; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Clinical genetics Molecular biology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Klinisk genetik Molekylärbiologi; MEDICINE Surgery Surgical research Orthopaedics; MEDICIN Kirurgi Kirurgisk forskning Ortopedi; MEDICINE Surgery Surgical research Transplantation surgery; MEDICIN Kirurgi Kirurgisk forskning Transplantationskirurgi; MEDICINE Morphology; cell biology; pathology Morphology Biomaterials; MEDICIN Morfologi; cellbiologi; patologi Morfologi Biomaterial; MEDICINE Morphology; cell biology; pathology; MEDICIN Morfologi; cellbiologi; patologi; NATURAL SCIENCES Biology Cell and molecular biology; NATURVETENSKAP Biologi Cell- och molekylärbiologi; NATURAL SCIENCES Chemistry Organic chemistry Polymer chemistry; NATURVETENSKAP Kemi Organisk kemi Polymerkemi; TECHNOLOGY Chemical engineering Chemical process and manufacturing engineering Materials chemistry; TEKNIKVETENSKAP Kemiteknik Kemisk process- och produktionsteknik Materialkemi; cellforskning; Cell Research; materialvetenskap; Materials Science; medicinsk cellbiologi; Medical Cell Biology; ortopedi; Orthopaedics;

    Abstract : The extracellular matrix is (ECM) is a network of large, structural proteins and polysaccharides, important for cellular behavior, tissue development and maintenance. Present thesis describes work exploring ECM as scaffolds for tissue engineering by manipulating cells cultured in vitro or by influencing ECM expression in vivo. READ MORE