Search for dissertations about: "MEDICINE Physiology and pharmacology Physiology Clinical physiology"
Showing result 1 - 5 of 6 swedish dissertations containing the words MEDICINE Physiology and pharmacology Physiology Clinical physiology.
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1. Vascular effects of neuropeptides and UDP-β-S and alterations after stroke
Abstract : The aim of this thesis is to investigate the changes in vasoactive intestinal peptide (VIP) and calcitonin gene-related peptide(CGRP) and P2Y6-mediated signaling following experimental subarachnoid hemorrhage (SAH) and transient middle cerebral artery occlusion (tMCAO). VIP and CGRP are among the most powerful vasodilators known to man while P2Y6 mediates strong vasoconstriction in cerebral blood vessels. READ MORE
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2. Brain glycine receptors as a common target for alcohol and the relapse-preventing drug acamprosate - a preclinical study
Abstract : Alcohol abuse and dependence make up the most prevalent categories of substance use disorders in the world. Converging evidence from the current research group has identified two receptor populations, the glycine (GlyRs) and nicotinic acetylcholine receptors (nAChRs) in the mesolimbic dopamine system, as two potentially important targets for the development of new medication to treat alcohol dependence. READ MORE
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3. Physiology and Pharmacology of GABAA receptors: The Brakes in the Brain
Abstract : Inhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). READ MORE
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4. Optimizing nicotinic acid delivery for durable antilipolysis and improved metabolic control
Abstract : Type 2 diabetes is a devastating disease affecting hundreds of millions worldwide. Lipid accumulation in peripheral non-adipose tissues is a major driver of insulin resistance, a central pathophysiological defect of this disease. READ MORE
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5. Blood Flow in Human Skeletal Muscle : The Effect of Adrenaline and the Influence of a Small Muscle Injury
Abstract : A variety of vasoregulatory systems are involved in the complex control of blood flow inhuman skeletal muscle. The interaction between these systems where one system canoverride or modify the other makes blood flow regulation complicated. READ MORE