Search for dissertations about: "MELANOMA-CELLS"

Showing result 1 - 5 of 46 swedish dissertations containing the word MELANOMA-CELLS.

  2. 1. Localization and expression of melanocortin receptors in melanoma cells, adrenal gland and brain

    Author : Yun Xia; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Abstract : .... READ MORE

  4. 2. Vitamin A and ß-carotene metabolism and effects of UV irradiation in human keratinocytes and melanocytes

    Author : Eva Andersson; Helen Håkansson; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Retinoids (vitamin A and its derivatives) are modulators of proliferation and differentiation. Both retinol (ROH) and its metabolite 3,4-didehydroretinol (ddROH) can be converted to retinoic acid (RA) and 3,4-didehydroretinoic acid (ddRA), ligands for the nuclear receptors, which induce gene transcriptions. READ MORE

  5. 3. Modulation of tumor sensitivity to effector mechanisms of cytotoxic lymphocytes

    Author : Kristian Hallermalm; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Tumor escape; cytotoxic lymphocytes; interferon-gamma; TNF-alpha; granzyme B; Perforin; Fas ligand;

    Abstract : Today, ample evidence demonstrates a clear role for the immune system in the battle against cancer. However, the relatively high rate of mutation and proliferation of tumor cells, in combination with the selective pressure exerted by the immune system, can potentially lead to the generation of genetically altered tumor cells, which are able to evade recognition by the immune system and continue to grow and form tumors. READ MORE

  6. 4. Inhibition of WNT5A Signaling and Function in Malignant Melanoma

    Author : Rickard Linnskog; Malmö Experimentell cancerforskning; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; WNT5A; Malignant Melanoma; Migration; Invasion; TGFβ; IL-6; p38-MAPK;

    Abstract : The life-threatening disease of malignant melanoma is one of the fastest growing forms of cancer, affecting an estimated number of 200,000 patients worldwide every year. Although highly curable if detected early, once the melanoma has metastasized there are few treatment options and a median survival rate of only 6-9 months. READ MORE

  7. 5. Parasite antigens and cellular interactions associated with the membrane of Plasmidium falciparum infected erythrocytes

    Author : Wipaporn Ruangjirachuporn; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : The asexual erythrocytic stages of malaria parasites are the cause of the pathological manifestations of the disease, Plasmodium falciparum being the species notorious for causing serious complications. This thesis describes studies on parasite-host cell interactions at two different stages of the P. READ MORE