Search for dissertations about: "MEMBRANE CURRENTS"

Showing result 1 - 5 of 29 swedish dissertations containing the words MEMBRANE CURRENTS.

  2. 1. Beyond AMPA and NMDA: Slow synaptic mGlu/TRPC currents : Implications for dendritic integration

    Author : Marcus Petersson; Erik Fransén; Abdel El Manira; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transient receptor potential; TRP; metabotropic glutamate receptor; mGlu1 5; dendritic integration; synaptic activation; temporal summation; low-frequency; entorhinal cortex; mathematical model; computational neuroscience; Computer science; Datavetenskap;

    Abstract : In order to understand how the brain functions, under normal as well as pathological conditions, it is important to study the mechanisms underlying information integration. Depending on the nature of an input arriving at a synapse, different strategies may be used by the neuron to integrate and respond to the input. READ MORE

  4. 2. Monopolar and Bipolar Membranes in Organic Bioelectronic Devices

    Author : Erik O. Gabrielsson; Magnus Berggren; Edwin Jager; Daniel Simon; Ari Ivaska; Linköpings universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; bioelectronics; ionic; ion transport; bipolar membrane; conjugated polymer; amyloid; self-assembly;

    Abstract : In the 1970s it was discovered that organic polymers, a class of materials otherwise best know as insulating plastics, could be made electronically conductive. As an alternative to silicon semiconductors, organic polymers offer many novel features, characteristics, and opportunities, such as producing electronics at low costs using printing techniques, using organic chemistry to tune optical and electronic properties, and mechanical flexibility. READ MORE

  5. 3. Dopaminergic and serotonergic modulation of cellular and locomotor network properties in the lamprey spinal cord

    Author : Martin Wikström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : 5-hydroxytryptamine; Dopamine; Calcium channels; Calcium-dependent potassium channels; Afterhyperpolarization; Membrane potential oscillation; Synaptic transmission; Modulation; Central pattern generator; Locomotion; Spinal cord; Lamprey;

    Abstract : Motor activity is the basis for all behavior. It is therefore important to study the processes generating movement such as the neuronal networks in the spinal cord that generates and controls locomotion. The lamprey is used as a model system for the study of locomotion. READ MORE

  6. 4. Roles of voltage-gated Ca2+ channel subunits in pancreatic β cells

    Author : Abdulla S. Kazim; Diabetes - öpatofysiologi; []
    Keywords : diabetes; Type 2 diabetes T2D ; Ca2 ; Ca2 channels; subunits;

    Abstract : Hallmarks of type 2 diabetes (T2D) include elevated blood glucose and free fatty acids (FFAs) as a result of impaired β cell insulin secretion and decreased β cell mass. The glucose-stimulated insulin secretion (GSIS) in β cells is triggered by depolarization-evoked Ca2+ entry through voltage-gated Ca2+ (CaV) channels. READ MORE

  7. 5. Patch-clamp studies of the GABAA receptor using microfluidic methods

    Author : Maria Millingen; Chalmers tekniska högskola; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; ion channel; microfluidics; GABAA receptor;

    Abstract : Ion channels are membrane proteins that passively transport ions. When activated, conformational changes within the protein lead to opening of a channel pore, and the flow of ions causes a change in the membrane potential. This is the fundamental process behind the generation and transduction of nerve impulses. READ MORE