Search for dissertations about: "MHC class 1"

Showing result 11 - 15 of 159 swedish dissertations containing the words MHC class 1.

  2. 11. Structural bases for MHC class I peptide selection and neoepitope formation

    Author : Ida Hafstrand; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : One task of the immune system is to distinguish between healthy cells and altered cells due to viruses or cancers. To achieve this CD8+ T-cells are constantly monitoring the Major histocompatibility class I (MHC-I) complexes expressed on all nucleated cells in the body. READ MORE

  4. 12. Staphylococcal enterotoxin H - structure and function of a superantigen

    Author : Helen Pettersson; Lunds universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; TCR; staphylococcal enterotoxin H; MHC class II; superantigen; transplantation; Immunologi; serologi; serology;

    Abstract : The aim of this thesis was to characterise the biological functions of the superantigen staphylococcal enterotoxin H (SEH). Superantigens are highly immunostimulatory proteins, which crosslink T cells and antigen presenting cells (APCs). READ MORE

  5. 13. Natural killer cell tolerance : influence of the MHC class I expression in the host

    Author : Maria H Johansson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : NK cells; MHC class 1; tolerance; transgenic mice; Ly49;

    Abstract : Development of self-tolerance in the immune system is characterized by somatic processes aiming at permanently eliminating, or silencing, potentially autoreactive lymphocytes. Such tolerance mechanisms are of outmost importance if autoimmunity is to be avoided. READ MORE

  6. 14. LIVING WITH PARASITES: AVIAN MALARIA, TELOMERE LENGTH AND LIFE HISTORY TRADE-OFFS

    Author : Asghar Muhammad; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Avian malaria; Plasmodium; qPCR; parasitemia; life history; reproduction; survival; feather growth; MHC; telomere length; heritability; telomere loss; fitness; wild population; Acrocephalus arundinaceus; Delichon urbica;

    Abstract : Haemosporidia is a well-studied group of parasites, which infect mammals, reptiles and birds and use blood sucking vectors for their transmission. By conducting natural population studies and experimental infections, We have been able to detect and quantify Haemosporidia from avian blood to investigate how these pathogens affect their avian hosts. READ MORE

  7. 15. Genetic Factors and Nasal Tolerance in Rat Models for Rheumatoid Arthritis

    Author : Shemin Lu; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nasal tolerance; linkage analysis; MHC; genetics; pristane induced arthritis; rheumatoid arthritis; collagen induced arthritis; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : We used three animal models of rats for rheumatoid arthritis (RA) in this study. Firstly, We found that CXI induced arthritis (CXIIA) is associated with the RT1 f haplotype and follows a chronic disease course affecting peripheral joints with both progression and relapses. READ MORE