Search for dissertations about: "MHC rat mouse transgenic autoimmunity collagen peptide"

Found 2 swedish dissertations containing the words MHC rat mouse transgenic autoimmunity collagen peptide.

  1. 1. MHC and Transgenic Mice. A study into polymorphism and function of class I and class II molecules

    Author : Mikael Vestberg; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MHC rat mouse transgenic autoimmunity collagen peptide; Clinical biology; Klinisk biologi;

    Abstract : Transplantation antigens encoded in the major histocompatibility complex (MHC) bind peptides and present them to T cells. We showed that mouse T cells expressing transgenic human CD8 can recognise human MHC class I. READ MORE

  2. 2. Arthritis Susceptibility and Tolerance in Collagen Transgenic Mice

    Author : Vivianne Malmström; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rheumatology locomotion; animal model arthritis collagen autoimmunity tolerance cartilage mice; muscle system; Skeleton; Skelett; muskelsystem; reumatologi;

    Abstract : This thesis is based on work trying to understand the normal and pathological interactions taking place between the immune system and cartilage, specifically involving the cartilage-specific protein typ II collagen (CII). The work has been carried out in an experimental model of rheumatoid arthritis namely collagen type II induced arthritis (CIA) in mice. READ MORE