Search for dissertations about: "MHC"

Showing result 6 - 10 of 374 swedish dissertations containing the word MHC.

  2. 6. Evolution of MHC Genes and MHC Gene Expression

    Author : Karin Berggren Bremdal; Hans Ellegren; Jennifer Seddon; Philip Hedrick; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; major histocompatibilty complex; dog leukocyte antigen; balancing selection; linkage disequilibrium; promoter; diabetes mellitus; Canis familiaris; Canis lupus; Erinaceus europaeus; Erinaceus concolor; Genetics; Genetik; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : Polymorphism in coding regions and regions controlling gene expression is the major determinant of adaptive differences in natural populations. Genes of the major histocompatibility complex (MHC) possess a high level of genetic variation, which is maintained by selection over long coalescence times. READ MORE

  4. 7. MHC diversity and expression in a songbird : Temporal and transgenerational variation

    Author : Samantha Mellinger; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MHC diversity; MHC-I gene expression; songbirds; genome assembly; amplicon HTS; temporal variation; family data; great reed warbler Acrocephalus arundinaceus ;

    Abstract : The immune system is of central importance to clear-off pathogens in order to keep an organism healthy. In vertebrates, the Major Histocompatibility Complex (MHC) is a genomic region that holds key genes involved in adaptive immunity and in particular in the antigen presenting process. READ MORE

  5. 8. Genetic Aspects of Sexual Selection and Mate Choice in Salmonids

    Author : Lars Forsberg; Mats Grahn; Jacob Höglund; Claus Wedekind; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; mate choice; Mhc; Major histocompatibility complex; class IIB; disassortative; assortative; microsatellite; outbreeding; supportive breeding; population; population genetics; Biologi; Biology; Biologi;

    Abstract : The long-term genetic consequences of supportive breeding programs are not well understood. Nevertheless, stocking populations with hatchery-produced fish to compensate for losses of natural production are common practice, for example after constructions of hydroelectric power dams. READ MORE

  6. 9. LIVING WITH PARASITES: AVIAN MALARIA, TELOMERE LENGTH AND LIFE HISTORY TRADE-OFFS

    Author : Asghar Muhammad; MEMEG; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Avian malaria; Plasmodium; qPCR; parasitemia; life history; reproduction; survival; feather growth; MHC; telomere length; heritability; telomere loss; fitness; wild population; Acrocephalus arundinaceus; Delichon urbica;

    Abstract : Haemosporidia is a well-studied group of parasites, which infect mammals, reptiles and birds and use blood sucking vectors for their transmission. By conducting natural population studies and experimental infections, We have been able to detect and quantify Haemosporidia from avian blood to investigate how these pathogens affect their avian hosts. READ MORE

  7. 10. Avian malaria, life-history trade-offs and interspecific competition in Ficedula flycatchers

    Author : Katarzyna Kulma; Anna Qvarnström; Marlene Zuk; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Blood parasites; competitive asymmetry; immunocompetence; interspecific competition; life-history trade-offs; MHC; parasite-driven selection;

    Abstract : This thesis investigates the impact of avian malaria (Haemosporidia) parasites on the outcome of interspecific competition between two closely related bird species, pied (Ficedula hypoleuca) and collared (F. albicollis) flycatchers. READ MORE