Search for dissertations about: "MIF"

Showing result 16 - 20 of 23 swedish dissertations containing the word MIF.

  2. 16. Chronic infection with chlamydia pneumoniae in COPD and lung cancer

    Author : Eva Brandén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chlamydia pneumoniae; chronic infection; lung cancer; COPD; treatment; detection;

    Abstract : Lung cancer and chronic obstructive pulmonary disease (COPD) are major causes of morbidity and mortality throughout the world. Smoking is the main cause for both diseases, but other factors seem to contribute. READ MORE

  4. 17. Formation of Composite Islet Grafts : A novel strategy to promote islet survival and revascularization

    Author : Ulrika Johansson; Peetra Magnusson; Korsgren Olle; Bo Nilsson; Federico Bertuzzi; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Islet of Langerhans; cytokines and cytokinereceptors expression; endothelial cells; mesenchymal stromal cells; transplantation; revascularization; Clinical immunology; Klinisk immunologi; cellforskning; cellforskning;

    Abstract : The islets of Langerhans are small and delicate spheroid organs scattered in the pancreas responsible for insulin production. Transplantation of isolated islets is a beneficial therapy for patients with a severe form of type 1 diabetes. READ MORE

  5. 18. Glioma as an Ecosystem : Studies of Invasion, Onco-miR Addiction and Mast Cell Infiltration

    Author : Jelena Põlajeva; Bengt Westermark; Ingemar Ernberg; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioblastoma; mast cell; miR-21; RAP1; CXCL12; SOX2;

    Abstract : Despite recent advances in oncology and extensive research efforts, gliomas remain essentially incurable. Glioblastoma multiforme (GBM, WHO grade IV) is the most common glioma and may arise de novo or progress from a lower-grade lesion. GBM is characterized by invasive growth, aberrant angiogenesis and necrosis. READ MORE

  6. 19. Immunoregulation in an experimental model of allergic asthma

    Author : Magnus Korsgren; Avdelningen för klinisk kemi och farmakologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; macrophage migration inhibitory factor; eosinophils; gd T cells; NK1.1 T cells; natural killer cells; immunoglobulins; B cells; innate immunity; allergic airway inflammation; immediate hypersensitivity; Physiology; Fysiologi; Immunology; serology; transplantation; Immunologi; serologi;

    Abstract : In allergic asthma the immune response to antigen is inappropriate, leading to an inflammatory process in the respiratory mucosa. To further elucidate immunological mechanisms involved in the development of such inflammation, control mice and mice deficient in selected cell types or proteins, were used in experimental models of allergic asthma and anaphylaxis. READ MORE

  7. 20. Sarcoma ecosystems : spatial characterization and prognostic significance

    Author : Yanhong Su; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Sarcoma is a highly heterogeneous disease with complex biological activities and unique tumor microenvironments (TME) in distinct subtypes. The limited treatment options and inadequate responses to current therapies necessitate a deeper understanding of sarcoma biology and personalized treatment strategies. READ MORE