Search for dissertations about: "MIP-2"

Showing result 21 - 25 of 27 swedish dissertations containing the word MIP-2.

  2. 21. Mechanisms of neutrophil recruitment in septic lung injury

    Author : Karzan Palani; Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; sepsis; infection; neutrophil; lung; chemokines; apoptosis; CD44; F-actin; peptides;

    Abstract : Sepsis is one of leading cause of death despite aggressive surgical intervention and antibiotic therapies. Excessive neutrophil recruitment is a major feature in early phase with immune system dysfunction at later phase. Lung is the most vulnerable, critical and sensitive organ during sepsis process. READ MORE

  4. 22. Immunoregulation and immunotherapy in experimental autoimmune neuritis

    Author : Li-Ping Zou; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Experimental autoimmune neuritis (EAN) is a CD4+ T cell mediated autoimmune disease of the peripheral nervous system (PNS). EAN represents an animal model for studying the immunopathogenesis and immunotherapy of Guillain-Barré syndrome (GBS). READ MORE

  5. 23. Human adipose tissue. Genes predominantly expressed in the visceral depot and in hypertrophic adipocytes

    Author : Jenny Palming; Göteborgs universitet; []
    Keywords : obesity; type 2 diabetes; adipose tissue depots; complement system; plasma cell; Fc receptor; serum amyloid A; NAD P H:quinone oxidoreductase 1; DNA microarray;

    Abstract : The obesity prevalence is increasing worldwide and obesity is closely linked to type 2 diabetes and cardiovascular disease. Both visceral fat accumulation and enlarged adipocyte size are risk factors for obesity related metabolic disorders. READ MORE

  6. 24. Pulmonary Injury Following Intestinal Ischemia and Reperfusion in Rats

    Author : Anna Börjesson; Lund Kirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; reperfusion injury; intestinal ischemia; pulmonary injury; endothelium; cytokines; alveolar fluid clearance; leukocytes; orthopaedics; Surgery; traumatology; ortopedi; Kirurgi; traumatologi;

    Abstract : Intestinal ischemia and reperfusion (I/R) is a potentially life-threatening condition, sometimes leading to a systemic inflammatory response and the potential development of the multiple organ dysfunction syndrome. The overall aim of the thesis was to study the effects of intestinal I/R on pulmonary function with special emphasis on removal of excess alveolar fluid, pulmonary endothelial barrier permeability, leukocyte accumulation and function, and possible therapeutic strategies to prevent the development of pulmonary injury following intestinal I/R. READ MORE

  7. 25. Studies on cytokines and chemokines in cerebrovascular diseases and experimental cerebral ischemia

    Author : Nikolaos Kostulas; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Ischemic brain injury secondary to arterial occlusion, a major cause of stroke, is characterized by acute local inflammation, which involves the accumulation of polymorphonuclear neutrophils and other immune cells. Tissue damage resulting from ischemic stroke can be reduced in experimental animal models by blocking leukocyte accumulation. READ MORE