Search for dissertations about: "MITF gene"
Showing result 6 - 10 of 10 swedish dissertations containing the words MITF gene.
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6. Regulation of B cell development by antigen receptors
Abstract : The developmental processes of lymphopoiesis generate mature B lymphocytes from hematopoietic stem cells through increasingly restricted intermediates. Networks of transcription factors regulate these cell fate choices and are composed of both ubiquitously expressed and B lineage-specific factors. READ MORE
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7. NotI genome scanning to identify unknown cancer associated genes in major human epithelial malignancies
Abstract : Epithelial cancers cause many deaths every year. Changes in the genes of human chromosome 3 are particularly common in epithelial cancers in several organs. Alterations in DNA methylation is one of the best known epigenetic changes in cancer. READ MORE
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8. Electrophysiology, Optical Coherence Tomography and Molecular Genetic Analysis in Patients with Glaucoma and/or Best Vitelliform Macular Dystrophy as Part of Clinical Care
Abstract : Glaucoma is a common ophthalmic disease with multifactorial aetiology. There is growing evidence that glaucoma is a disease of the entire retina and not only the inner retina. READ MORE
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9. Molecular genetics and mechanisms of pigmentation and melanoma
Abstract : Ever since man domesticated the first wild animals several thousand years ago, many species have been living in close relationship with humans, being objects for our requests and wishes about any kind of phenotypic traits. As a result, we have by selective breeding created a fascinating spectrum of phenotypes within most species we have domesticated. READ MORE
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10. Unravelling molecular mechanisms underlying therapy resistance in cutaneous melanoma
Abstract : For many years the standard treatment of advanced metastatic melanoma with chemotherapeutic agents, including temozolomide (TMZ) and dacarbazine (DTIC), has been unsuccessful. The paradigm shift in melanoma treatment occurred with the identification of mutations in the BRAF gene that leads to a constitutively active BRAF V600E protein. READ MORE