Search for dissertations about: "MMCP"

Showing result 1 - 5 of 11 swedish dissertations containing the word MMCP.

  2. 1. Neutral proteases of rodent mast cells

    Author : Carolina Lunderius; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Mast cell; serine protease; MMCP; RMCP; heparin; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; immunologi; Immunology;

    Abstract : Mast cells are important effector cells in general as well as in allergic inflammation andin the defence against helminthic parasites and bacteria. Two major populations, withdifferences in tissue distribution, have been identified; connective tissue mast cells andmucosal mast cells. READ MORE

  4. 2. Chymotrypsin/trypsin-related serine proteases : A structural, functional and evolutionary analysis

    Author : Maryam Poorafshar; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; serine proteases; proteoglycans; mast cells; basophils; Biokemi; Biochemistry; Biokemi; immunologi; Immunology;

    Abstract : Is life possible without proteolytic enzymes? Proteases participate in almost everyaspect of life and they can be found throughout the body and in every cell. Mast cells,together with basophils are, two important effector cells of the immune system. READ MORE

  5. 3. The role of mast cell proteases in allergic disease and apoptosis

    Author : Ida Waern; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Abstract : Mast cells (MCs) are key effector cells in allergic reactions, through the release of a wide variety of granule-stored and de novo synthesized inflammatory mediators. The MC secretory granules contain exceedingly high levels of serglycin proteoglycan and the heparin-binding proteases chymase, tryptase and carboxypeptidase A. READ MORE

  6. 4. Serglycin-dependent mast cell-specific proteases and their potential interactions with Giardia intestinalis

    Author : Zhiqiang Li; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Mast cells are located in mucosal and connective tissues throughout the body where they play important roles in immune reactions towards infections. Mast cell deficiency results in failure of clearance of the non-invasive intestinal protozoan parasite Giardia intestinalis in mice, but the mast cell-driven mechanisms remain poorly understood. READ MORE

  7. 5. The Role of Fc gamma Receptors and Mast Cell Chymase in Autoimmune Arthritis

    Author : Sofia Magnusson; Sandra Kleinau; Jeanette Leusen; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; fc gamma receptors; rheumatoid arthritis; antibodies; mast cells; mast cell; Immunology; Immunologi; Immunologi; Immunology;

    Abstract : In autoimmune diseases such as rheumatoid arthritis (RA), self-reactive antibodies are present at high levels, which contributes to disease pathogenesis. The antibodies mediate their effect predominantly by binding to Fc gamma receptors (FcγR) on various leukocytes, such as monocytes, macrophages and mast cells, where FcγR ligation leads to cell activation. READ MORE