Search for dissertations about: "MMTV"

Showing result 1 - 5 of 15 swedish dissertations containing the word MMTV.

  2. 1. Human mouse mammary tumor virus like elements and their relations to breast cancer

    Author : Hong Yin; Uppsala universitet; []
    Keywords : Medical sciences; human MMTV like sequence HML ; human breast cancer; expression of HML; integration of HML sequence; localization of HML-6; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; mikrobiologi; Microbiology;

    Abstract : The human genome contains a variety of more or less ancient endogenous retroviral sequences. They are commonly referred to as HERVs (human endogenous retroviruses). Of all the known HERV groups, the HERV-K supergroup apparently comes closest to encoding functional retroviral proteins, although infectious particles have not been demonstrated. READ MORE

  4. 2. Transcription factor effects on chromatin organisation and gene regulation

    Author : Per-Henrik Holmqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Chromatin; enhanceosome; MMTV; GR; NF1; Oct1; FoxA;

    Abstract : The intranuclear DNA of all eukaryotic cells is packed into chromatin, generating a repressive environment for the genome. Remodelling of the local chromatin structure is a vital process that allows access to the obscured DNA sequence and may induce the expression of specific genes. READ MORE

  5. 3. Studies on nuclear factor 1 binding to nucleosomal DNA

    Author : Patrik Blomquist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : nuclear factor 1; nucleosome; glucocorticoid receptor; triplex DNA; the SWISNF complex; A-tracts; MMTV LTR;

    Abstract : The organisation of DNA into chromatin will influence on transcriptional regulation. The first event in transcriptional activation is the binding of transcription factors to specific binding sites in the regulatory regions of the gene. READ MORE

  6. 4. Chromatin remodelling and gene regulation

    Author : Birgitta Gelius; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Chromatin plays an important role in gene regulation, as it forms an obstacle for a number of proteins that need access to the DNA. Several protein complexes that open up the chromatin structure have been identified and some of these are important for gene regulation. READ MORE

  7. 5. Viral dUTPases, Recombinant Expression, Purification and Characterization

    Author : Anna-Carin Bergman; Biokemi och Strukturbiologi; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Proteins; nucleocapsid protein; retrovirus; herpesvirus; dUTPase; nucleotide metabolism; enzymology; Proteiner; enzymologi;

    Abstract : The enzyme deoxyuridine 5’-triphosphate nucleotidohydrolase (dUTPase, EC 3.6.1.23) catalyzes the hydrolysis of dUTP to dUMP and pyrophosphate. READ MORE