Search for dissertations about: "MOI"

Showing result 16 - 18 of 18 swedish dissertations containing the word MOI.

  1. 16. Characterization of the attenuated Francisella tularensis strain FSC043 : with special focus on the gene pdpC

    Author : Marie Lindgren; Anders Sjöstedt; Marina Santic; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Francisella tularensis; intracellular bacteria; J774; apoptosis; pyroptosis; PdpC; FSC043; Clinical Bacteriology; klinisk bakteriologi; mikrobiologi; Microbiology;

    Abstract : Francisella tularensis is a highly infective, intracellular bacterium. It is capable of infecting a wide range of mammals and causes the disease tularemia in humans. As a result of its high infectivity there have been a lot of efforts made to create a generally available vaccine against this pathogen. READ MORE

  2. 17. Making visible the invisible : Health risks from environmental exposures among socially deprived populations of Nairobi, Kenya

    Author : Thaddaeus Wandera Egondi; Joacim Rocklöv; Nawi Ng; Remare Ettarh; Patrick Kinney; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; air pollution; urban health; temperature-related mortality; particulate matter; exposure assessment; child health; Epidemiology; epidemiologi; folkhälsa; Public health;

    Abstract : Background: Most countries of sub-Saharan Africa (SSA) are experiencing a high rate of ur­banization accompanied with unplanned development resulting into sprawl of slums. The weath­er patterns and air pollution sources in most urban areas are changing with significant effects on health. READ MORE

  3. 18. Physiological and clinical studies of calcium-regulating hormones calcitonin and parathyroid hormone-related protein

    Author : Haiqin Rong; Karolinska Institutet; Karolinska Institutet; []
    Keywords : bone metabolism; breast cancer; calcitonin; calcium; exercise; lanthanide; milk; neonate; osteoporosis; parathyroid hormone-related protein; parturition; polymerase chain reaction; time-resolved fluorometry;

    Abstract : The present studies were performed to elucidate several physiological and clinical questions of calcitonin (CT) and parathyroid hormone-related protein (PTHrP) such as: a) Does age influence the basal and calcium-stimulated levels and circulating molecular forms of CT in healthy females? b) Are osteoporotic patients lacking circulating monomeric CT? c) How is salmon CT (sCT) absorbed and cleared during treatment of diseases? d) Is there any effect of acute physical activity on circulating CT, PTH, PTHrP and bone metabolic markers? e) Is there an absorbance of PTHrP in milk by the neonate? and f) Are there any interactions between CT and PTHrP? In addition, by use of time-resolved dissociation and enhancement lanthanide fluorometry, the effort was put to develop two-site immunofluorometric assays (IFMA) for sCT and PTHrP as well as a quantitative competitive PCR (QC-PCR) for measuring PTHrP mRNA and use these methods in some of the investigations. Heterogeneity of CT forms in serum was disclosed after immunoextraction, fast protein liquid chromatography (FPLC) and radioimmunoassay (RIA) in healthy females and osteoporotic patients. READ MORE