Search for dissertations about: "MOLECULAR-MECHANISMS"

Showing result 1 - 5 of 737 swedish dissertations containing the word MOLECULAR-MECHANISMS.

  2. 1. Cytochrome c Oxidase dysfunction in cancer : Exploring the molecular mechanisms

    Author : Ida Namslauer; Peter Brzezinski; Susanne Arnold; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; biokemi;

    Abstract : Mutations in genes encoding the mitochondrial enzyme Cytochrome c Oxidase (CytcO) have lately been found in connection to various types of cancer. Some mutations result in substitutions of highly conserved amino-acid residues. READ MORE

  4. 2. From Food Preference to Craving : Behavioural Traits and Molecular Mechanisms

    Author : Johan Alsiö; Helgi B Schiöth; Jonas Lindblom; Anna M Kindlundh-Högberg; Suzanne Dickson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obesity; Reward; Food preferences; Dietary fats; Dietary carbohydrates; Anxiety; Dopamine; Craving; Operant self-administration; Pharmacology; Farmakologi; Farmakologi; Pharmacology;

    Abstract : Preference for palatable and energy-dense foods may be a risk factor for body weight gain and has both genetic and environmental components. Once obesity develops in an individual, weight loss is difficult to achieve. READ MORE

  5. 3. Molecular mechanisms of cardiovascular calcification

    Author : Miguel Carracedo Ortiz; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cardiovascular calcification is a pathophysiological process characterized by the deposition of calcium-phosphate crystals in the arteries and the leaflets of the heart valves. In the arteries calcification causes arterial stiffness, which may lead to poor cardiac perfusion, systolic hypertension and heart failure. READ MORE

  6. 4. Molecular mechanisms in cervical carcinogenesis : Studies of clonality, somatic genetic alterations and human papillomavirus variants in cervical pre-invasive and invasive cancer

    Author : Zhongmin Guo; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cervical cancer; CIN; clonality; X-chromosome inactivation; LOH; HPV; chromosome 3p; chromosome 6; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Abstract : Cervical cancer derives from a series of pre-invasive cervical neoplastic lesions termed CIN I-III (Cervical Intraepithelial Neoplasia) via typical multiple-step processes. In contrast to premalignant disorders in other organs, different degrees of CIN possess a distinct biological behaviour where a proportion spontaneously regress or persist, whereas some progress to invasive cancer. READ MORE

  7. 5. Molecular mechanisms in vascular inflammation

    Author : Peder S Olofsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Vascular inflammation plays an important role in a multitude of major diseases including sepsis and atherosclerosis. Sepsis has been estimated to account for more than 100 000 deaths per year in Europe. READ MORE