Search for dissertations about: "MOLECULES PARTICIPATE"

Showing result 1 - 5 of 61 swedish dissertations containing the words MOLECULES PARTICIPATE.

  1. 1. Defining Regulators of Human Hematopoietic Stem Cells

    Author : Christine Karlsson; Avdelningen för molekylärmedicin och genterapi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; High-throughput screening; Expansion; Hematopoietic stem cell; Cord blood; RNA interference; extrinsic Signaling molecules;

    Abstract : Bone marrow transplantation (BMT) is a conceptual and elegant example of stem cell therapy, rendered possible by the dual capacity of hematopoietic stem cells (HSCs) to self-renew and differentiate. These defining features ultimately ensure the production of all blood cell lineages and simultaneous maintenance of the stem cell pool, thereby maintaining lifelong homeostasis. READ MORE

  2. 2. Regulation of signaling molecules in sensory neurons and spinal cord : studies on nerve injury models and transgenic mice

    Author : Tie-Jun Shi; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Behaviour; cell loss; dorsal root ganglion; immunohistochemistry; in situ hybridization; mRNA; nerve injury; neuropathic pain; neuropeptides; nociception; primary sensory neuron; spinal cord.;

    Abstract : Nerve injury may cause neuropathic pain in patients. Similar symptoms can also be seen in some animal models. READ MORE

  3. 3. Distribution and connectivity of messenger molecules in the control of energy metabolism : focus on neuropeptides and calcium binding proteins

    Author : Kylie S Foo; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Feeding is an essential and complex behavior which aims to provide the energy required for maintaining physiological homeostasis. The drive to feed is a powerful stimulus arising from metabolic demands, and reinforced by evolutionary pressure. READ MORE

  4. 4. Functional and structural characterization of integrins and their ligands ICAM-2, vitronectin and fibronectin in leukocytes

    Author : Rosalba Salcedo Amaya; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Leukocytes; Adhesion molecules; Integrins; ICAM-2; Vitronectin; Fibronectin.;

    Abstract : Transient adhesion of leukocytes to cells and extracellular matrices is a crucial process in leukocyte physiology. Cell surface adhesion molecules such as integrins and members of the immunoglobulin (Ig) superfamily are involved. READ MORE

  5. 5. Surface-Induced Modification of Supported Late Transition Metal Complexes

    Author : Olesia Snezhkova; Synkrotronljusfysik; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; N-heterocyclic carbene palladium complexes; X-ray photoelectron spectroscopy; electron charge transfer; iron phthalocyanine; catalysis; X-ray absorption spectroscopy;

    Abstract : The work presented in this thesis addresses the investigation of the electronic, magnetic, and structural properties of late transition metal complexes supported on various surfaces. The research is aimed at studying the interaction between the molecules and the support, together with the intermolecular interaction. This knowledge is essential e.g. READ MORE