Search for dissertations about: "MRI multiple sclerosis"

Showing result 1 - 5 of 41 swedish dissertations containing the words MRI multiple sclerosis.

2. 1. Quantitative MRI Biomarkers of Neurodegeneration in Multiple Sclerosis

   Author : Michael Platten; Tobias Granberg; Chunliang Wang; Fredrik Piehl; Sara Shams; Mattias Vågberg; KTH; Karolinska Institutet; Karolinska Institutet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Machine learning; Multiple sclerosis; Corpus callosum; Neurodegeneration; Medical Technology; Medicinsk teknologi;

   Abstract : Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease that targets myelin in the brain and spinal cord. The corpus callosum connects the cerebral hemispheres and is composed of heavily myelinated axons. READ MORE

4. 2. MRI quantification of multiple sclerosis pathology

   Author : Russell Ouellette; Karolinska Institutet; Karolinska Institutet; []
   Keywords : ;

   Abstract : Background: Multiple sclerosis (MS) is a chronic neuroinflammatory and neurodegenerative disease and a common cause of neurologic disability. MS pathology is characterized by demyelination, neuroaxonal loss and atrophy. READ MORE

5. 3. Diagnostic, prognostic and management aspects of different types of multiple sclerosis

   Author : Petra Nilsson; Lund Neurologi; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; optic neuritis; multiple sclerosis; cerebrospinal fluid; magnetic resonance imaging; prognosis; cognition; diagnosis; primary progressive multiple sclerosis; tumefactive MS; craniectomy;

   Abstract : Background: The aim in the thesis is to study diagnostic issues, clinical features, therapy, and prognosis in selected demyelinative disorders of the nervous system: optic neuritis (ON), primary progressive MS (PPMS), and tumefactive MS (a very rare acute demyelinating disorder). Methods: From an initial cohort of 110 patients with ON collected 19 to 31 years ago, a new follow-up survey was conducted in 50 patients who on a previous follow up had not developed MS. READ MORE

6. 4. Biomarkers and Disease Activity in Multiple Sclerosis : A cohort study on patients with clinically isolated syndrome and relapsing remitting multiple sclerosis

   Author : Irene Håkansson; Jan Ernerudh; Charlotte Dahle; Magnus Vrethem; Jan Lycke; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Abstract : This thesis focuses on disease activity in clinically isolated syndrome (CIS) and newly diagnosed relapsing remitting multiple sclerosis (RRMS). The papers are based on data from 41 patients in a prospective longitudinal cohort study. All patients were untreated at baseline. READ MORE

7. 5. Treatment with the monoclonal antibody rituximab in Multiple Sclerosis : a study based on an academic clinical trial

   Author : Pierre de Flon; Anders Svenningsson; Martin Gunnarsson; Katarina Laurell; Sten Fredrikson; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Multiple sclerosis; Rituximab; Cytokines; Immunological profile; Neurofilament light; Treatment satisfaction; neurologi; Neurology;

   Abstract : Background: Multiple sclerosis (MS) is a chronic, inflammatory disease, affecting the central nervous system. A growing number of disease modifying treatment alternatives entails a need for an individualised risk-benefit- convenience analysis in the counselling of patients and methods to monitor the treatment effect, including markers for subclinical inflammation. READ MORE