Search for dissertations about: "MS2"

Showing result 1 - 5 of 21 swedish dissertations containing the word MS2.

  1. 1. Structure of small RNA phages

    Author : Kaspars Tars; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; bacteriophage; MS2; virus assembly; structural evolution; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; molekylärbiologi; Molecular Biology;

    Abstract : Small RNA phages belonging to the family Leviviridae are among the simplest known viruses. They have been used extensively as models for studies of various problems in molecular biology, including protein-RNA interactions, repression of translation, virus assembly and virus evolution. READ MORE

  2. 2. The Modular Domain Structure of ASF/SF2: Significance for its Function as a Regulator of RNA Splicing

    Author : Vita Dauksaite; Göran Akusjärvi; Javier Caceres; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; pre-mRNA splicing; alternative splicing; splicing regulation; SR proteins; ASF SF2; modular domains; adenovirus; MLTU L1; E1A; MS2; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : ASF/SF2 is an essential splicing factor, required for constitutive splicing, and functioning as a regulator of alternative splicing. ASF/SF2 is modular in structure and contains two amino-terminal RNA binding domains (RBD1 and RBD2), and a carboxy-terminal RS domain. READ MORE

  3. 3. RNA-protein interactions in the bacteriophage MS2

    Author : Elin Grahn; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molecular Biotechnology; molekylär bioteknik avd f jonfysik ;

    Abstract : The bacteriophage MS2 coat protein interacts specifically with a 19 nucleotide long hairpin formed within the viral RNA genome. In the current work the structural details of this interaction have been examined using X-ray crystallography of complexes where the RNA hairpin sequence has been varied. READ MORE

  4. 4. The three-dimensional structure of the bacteriophage MS2

    Author : Karin Valegård; Uppsala universitet; []

    Abstract : .... READ MORE

  5. 5. Machine Learning methods in shotgun proteomics

    Author : Patrick Truong; Lukas Käll; Peter Nilsson; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; mass spectrometry protein summarization Bayesian hierarchical modelling label-free quantification data-independent acquisition mass spectrometry; benchmark mathematical methods; transformers; computational proteomics; proteomics; bioinformatics; bert; ms2 intensity; probabilistic modelling; Biotechnology; Bioteknologi;

    Abstract : As high-throughput biology experiments generate increasing amounts of data, the field is naturally turning to data-driven methods for the analysis and extraction of novel insights. These insights into biological systems are crucial for understanding disease progression, drug targets, treatment development, and diagnostics methods, ultimately leading to improving human health and well-being, as well as, deeper insight into cellular biology. READ MORE