Search for dissertations about: "MTHFR"

Showing result 1 - 5 of 20 swedish dissertations containing the word MTHFR.

  1. 1. Genetic variation in the folate receptor-alpha and methylenetetrahydrofolate reductase genes as determinants of plasma homocysteine concentrations

    University dissertation from Örebro : Örebro universitet

    Author : Anna Böttiger; Örebro universitet.; [2008]
    Keywords : LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Folate receptor-alpha; Folate; FOLR1; Haplotypes; Homocysteine; Methylenetetrahydrofolate reductase; MTHFR; Polymorphisms; Pyrosequencing®; SSCP; VETERINARY MEDICINE Medicine; VETERINÄRMEDICIN Medicin; Biomedicin; Biomedicine;

    Abstract : Elevated total plasma homocysteine (tHcy) is a risk factor for cardiovascular disease and neurocognitive disease such as dementia. The B vitamins folate and B12 are the main de terminants of tHcy. tHcy concentration can also be affected by mutations in genes coding for receptors, enzymes and transporters important in the metabolism of Hcy. READ MORE

  2. 2. Homocysteine and vascular morbidity and dementia in women. A prospective population study

    University dissertation from Göteborg : Intellecta

    Author : Dimitri Zylberstein; Göteborgs universitet.; Gothenburg University.; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Women; population study; dementia; Homocysteine; MTHFR; myocardial infarctions; lacunar infarcts; epidemiology;

    Abstract : Homocysteine and cardiovascular morbidity and dementia in women - A prospective population study Dimitri Edin Zylberstein Institute of Medicine, The Sahlgrenska Academy, Department of Public Health and Community Medicine, Section of Primary Health Care, University of Gothenburg Abstract Purpose. The purpose of this thesis was to study cardiovascular morbidity and dementia in relation to homocysteine levels in women in a longitudinal, prospective population study over several decades. READ MORE

  3. 3. Coffee and gene interaction. The effect on methionine and lipid metabolism

    University dissertation from Göteborg : Intellecta

    Author : Elisabeth Strandhagen; Göteborgs universitet.; Gothenburg University.; [2004]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; coffee; homocysteine; cholesterol; folate; pyridoxine; MTHFR; APOE; gene; polymorphism; interaction;

    Abstract : Background: Different dietary factors influence the risk of coronary heart disease (CHD), most likely in an interaction with genetic polymorphisms. The knowledge about such interactions is insufficient. Some observational studies have shown an association between coffee and CHD, others have not. Coffee consumption affects some CHD risk factors, e. READ MORE

  4. 4. Folates in the treatment of colorectal cancer

    University dissertation from Göteborg : University of Gothenburg

    Author : Helena Taflin; Göteborgs universitet.; Gothenburg University.; [2014]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Folate; Colorectal cancer; leucovorin; modufolin; LC-MS MS; polymorphisms; MTHFR; adjuvant chemotherapy;

    Abstract : ABSTRACT Folates in the Treatment of Colorectal Cancer Department of Surgery Institute of Clinical Sciences at Sahlgrenska Academy University of Gothenburg Helena Taflin Background: Colorectal cancer is one of the most common cancers in the world, and radical surgery with total removal of the tumour (RO-resection) is the single most important treatment. However, chemotherapy is recommended for patients with risk factors and patients with metastatic disease. READ MORE

  5. 5. Risk markers for a first myocardial infarction

    University dissertation from Umeå : Folkhälsa och klinisk medicin

    Author : Anna Margrethe Thøgersen; Umeå universitet.; [2005]
    Keywords : haemostatis; lipoprotein a ; MTHFR; homocysteine; proinsulin; leptin; apolipoprotein A1; DHEAS; myocardial infarction; risk factors;

    Abstract : The development of a first myocardial infarction is associated with a large number of contributing factors. Age, male sex, hypertension, smoking, diabetes, body mass index and hypercholesterolemia are considered as established risk factors. READ MORE