Search for dissertations about: "MUC2"

Showing result 16 - 20 of 22 swedish dissertations containing the word MUC2.

  2. 16. Evolution of Transmembrane and Gel-forming Mucins Studied with Bioinformatic Methods

    Author : Tiange Lang; Göteborgs universitet; []
    Keywords : ;

    Abstract : All mucosal membranes of the body are covered by mucus, largely made up of the family of large glycoproteins called mucins. These are instrumental for the protection of the underlying epithelia and involved in the pathogenesis of many diseases in the lungs and the intestine. READ MORE

  4. 17. Defence capabilities of human intestinal epithelial cells

    Author : Anna Fahlgren; Sten Hammarström; Marie-Louise Hammarström; Gudmundur Gudmundsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; intestine; mucosa; epithelium; antimicrobial; defensins; glycocalyx; ulcerative colitis; Crohn´s disease; celiac disease; Immunologi; Immunology; Immunologi; immunologi; Immunology;

    Abstract : The epithelial cells lining the intestinal mucosa separate the underlying tissue from components of the intestinal lumen. Innate immunity mediated by intestinal epithelial cells (IECs) provides rapid protective functions against microorganisms. Innate immunity also participates in orchestrating adaptive immunity. READ MORE

  5. 18. Helicobacter pylori binding to gastric mucins and host glycosylation changes after inoculation

    Author : Sara Lindén; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper allmänt ; General biomedical sciences; host-parasite interactions; H. pylori adhesin; mucin; Lewis antigen;

    Abstract : Helicobacter pylori may cause gastritis, gastric/duodenal ulcer and gastric cancer. During infection, most H. pylori are found in the gastric mucus layer, but some are attached to, or have penetrated, epithelial cells. The aim of this study is to characterize the binding of H. READ MORE

  6. 19. Studies towards ß-turn mimetics, synthesis of kedarosamine from threonine, and synthesis of glycopeptides from mucins and gp120

    Author : Tatjana Vuljanic; Centrum för analys och syntes; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Tn antigen; glycopeptides; glycosylation; diastereselective reduction; kedarosamine; kedarcidin chromophore; amino acids; peptide T; ß-turn mimetic; Organisk kemi; gp120; Organic chemistry;

    Abstract : The secondary structure of proteins is crucial for proper function of the protein in biological systems. Peptide T, an octapeptide from the envelope glycoprotein gp120 of the HIV virus, has previously been shown to be responsible for binding to the CD4 receptor on T helper/inducer lymphocytes. READ MORE

  7. 20. Mucins, Cystic Fibrosis and PDZ protein interactions

    Author : Emily Malmberg; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucin; PDZ; transmembrane; MUC1; Cystic Fibrosis; clathrin; CFTR; PDZK1; Bcr; endocytosis; MUC17;

    Abstract : Cystic Fibrosis (CF) is caused and characterized by mutations in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene. The dominating feature of the disease is mucus accumulation on mucosal surfaces, but no direct functional connection between mucus and CFTR is known. READ MORE