Search for dissertations about: "MYPT1"

Found 4 swedish dissertations containing the word MYPT1.

  2. 1. Signal transduction and calcium sensitivity of smooth muscle contraction

    Author : Johan Bonnevier; Institutionen för experimentell medicinsk vetenskap; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Fysiologi; Physiology; hypertrophy; CPI-17; MYPT1; myosin phosphatase; Rho kinase; PKC; smooth muscle; cGK;

    Abstract : Smooth muscles are components of several physiologically important organs and often involved in disease. Smooth muscle contraction is regulated by variations in intracellular [Ca2+]; increased levels activate the myosin light chain kinase (MLCK) which phosphorylates myosin and initiates contraction. READ MORE

  4. 2. Developmental regulation of smooth muscle contraction in the urinary bladder

    Author : Mari Ekman; Cellulär biomekanik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; newborn; Rho-kinase; cellular signaling; muscarinic receptors; calcium sensitivity; protein kinase C; non-muscle myosin; myosin light chain phosphatase;

    Abstract : Smooth muscle cells in the urinary bladder are involved in the control of urine filling and emptying. We have used mice to study the contractile regulation of urinary bladder smooth muscle during the fetal period. READ MORE

  5. 3. α1-acid glycoprotein modulates the function of human neutrophils and platelets

    Author : Peter Gunnarsson; Magnus Grenegård; Henrik Thorlacius; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : The acute-phase protein α1-acid glycoprotein (AGP; orosomucoid) was initially identified andcharacterised in the 1950s. The normal plasma concentration is around 0.5-1 mg/ml butduring inflammation the concentration increase several fold and the carbohydrate compositionof the protein changes. READ MORE

  6. 4. Cell signaling and regulation of smooth muscle contraction from a physiological and a pathophysiological perspective

    Author : Lena Boberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : The aim of this thesis was to examine the cell signaling and regulation of smooth muscle in different smooth muscle tissues and under pathophysiological conditions. The thesis is based on 4 papers and the experimental work is based on in vitro studies in mouse. READ MORE