Search for dissertations about: "Macrophages drug effects"

Showing result 1 - 5 of 30 swedish dissertations containing the words Macrophages drug effects.

  2. 1. Cancer and Inflammation : Role of Macrophages and Monocytes

    Author : Alexander Hedbrant; Jonny Wijkander; Dick Delbro; Ann Erlandsson; Anita Sjölander; Karlstads universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; M1 macrophages; M2 macrophages; colon cancer; lung cancer; prostaglandin E2; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Macrophages are cells of the innate immune system that can be found in large quantities in cancer tumors and affect cancer progression by regulating growth and invasiveness of cancer cells. There are two main phenotypes of macrophages denoted M1 and M2. READ MORE

  4. 2. Adverse drug effects on glucose and lipid metabolism: is human adipose tissue of importance?

    Author : Assel Sarsenbayeva; Jan Eriksson; Mikael Rydén; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human adipose tissue; metabolic adverse effects; SGAs; statins; glucocorticoids; glucose uptake; lipolysis; myofibroblasts; fibrosis; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

    Abstract : Many pharmacological agents that are widely prescribed in clinical practice have adverse metabolic effects, such as hyperglycaemia, insulin resistance, and diabetes. Among such drugs are antipsychotics, prescribed for treatment of schizophrenia; statins, which inhibit cholesterol synthesis and prevent cardiovascular events; finally, potent anti-inflammatory agents, glucocorticoids. READ MORE

  5. 3. Accelerated wound healing by on-site production and delivery of CXCL12

    Author : Emelie Öhnstedt; Mia Phillipson; Uppsala universitet; []
    Keywords : wound healing; non-healing wounds; L. reuteri; macrophages; wound assessment; Fysiologi; Physiology;

    Abstract : Non-healing wounds is a growing medical problem, often associated with pathological conditions such as diabetes and peripheral ischemia. A non-healing wound entails a large amount of suffering for the patient, and demands extensive health care resources. READ MORE

  6. 4. Interplay of human macrophages and Mycobacterium tuberculosis phenotypes

    Author : Johanna Raffetseder; Maria Lerm; Olle Stendahl; Vesa Loitto; Trude Helen Flo; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mycobacterium tuberculosis; tuberculosis; macrophage; innate immunity; host-pathogen interaction; antibiotic tolerance; phagosomal maturation; bacterial phenotype; dormancy; persistence; virulence factor; ESAT-6; ESX-1;

    Abstract : Mycobacterium tuberculosis (Mtb) is the pathogen causing tuberculosis (TB), a disease most often affecting the lung. 1.5 million people die annually due to TB, mainly in low-income countries. READ MORE

  7. 5. Electropermeabilization in Experimental Tumour Treatment: Dosimetry and Tissue Effects

    Author : Per Engström; Lund Medicinsk strålningsfysik; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; liver; electroporation; ischemia; Electropermeabilization; ECT; Tumor; 111-In-BLMC; 99m-Tc-DTPA; glioma; rat; electric pulses; Impedance spectrometry; treatment; Physics; Fysik;

    Abstract : Short, electric high-voltage pulses can be used to transiently increase the permeability of cell membranes without significant loss of cell viability. During this period of time, extracellular and normally non-permeant, molecules are accessed the cytoplasm and the cell nucleus. READ MORE