Search for dissertations about: "Macrophages pathology"

Showing result 11 - 15 of 55 swedish dissertations containing the words Macrophages pathology.

  2. 11. Oxidized Lipids and Lysosomal Pathology in Atherogenesis

    Author : Wei Li; Wendy Jessup; Linköpings universitet; []
    Keywords : MEDICINE; MEDICIN;

    Abstract : Macrophages take up large amount of exogenous materials such as oxidatively modified low-density lipoproteins (oxLDL) and lysosomotropic agents. OxLDL is taken up into macrophage lysosomes through receptor-mediated endocytosis, but poorly degraded, resulting in foam cell formation. READ MORE

  4. 12. Innate immunity in Staphylococcus aureus arthritis and sepsis

    Author : Margareta Verdrengh; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Staphylococcus aureus; mice; sepsis; septic arthritis; neutrophils; monocytes macrophages; GM-CSF; adhesion molecules;

    Abstract : Bacterial arthritis is a severe, rapidly progressing erosive disease with high morbidity and mortality. Staphylococcus aureus is the most common causative bacterium. Granulocytes together with cells from the monocyte/macrophage lineage, are the earliest leukocytes entering the synovial tissue in response to invading staphylococci. READ MORE

  5. 13. Investigations of Proneural Glioblastoma to Identify Novel Therapeutic Targets

    Author : Maria Boije; Lene Uhrbom; Bengt Westermark; Rolf Bjerkvig; Uppsala universitet; []
    Keywords : Glioma; proneural subtype; hallmarks; glioma initiating cells; S-SOX5; angiogenesis; stromal cells; Tumour biology; Tumörbiologi; Experimentell patologi; Experimental Pathology;

    Abstract : Malignant glioma is a highly lethal and destructive disease with no proper cure. We have investigated some of the hallmarks of cancer in connection to glioma and found ways to disrupt these and prevent tumor growth. The work is done within the context of a glioma subtype distinguished by activation of PDGF signaling termed the proneural subtype. READ MORE

  6. 14. The Importance of Macrophages, Lipid Membranes and Seeding in Experimental AA Amyloidosis

    Author : Aida Vahdat Shariatpanahi; Karin Öllinger; Katarzyna Lundmark; Gunilla Westermark; Elin Esbjörner Winters; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Amyloidosis is a group of protein misfolding diseases caused by tissue deposition of fibrillary protein aggregates termed amyloid. Amyloid A (AA) amyloidosis is a systemic form of amyloidosis that occurs as a complication of chronic inflammatory diseases, such as rheumatoid arthritis, familial Mediterranean fever and chronic infections, such as tuberculosis. READ MORE

  7. 15. Chemoattractants as causative agents, biomarkers and therapeutic targets in vascular pathology

    Author : Yuri Sheikine; Karolinska Institutet; Karolinska Institutet; []
    Keywords : atherosclerosis; coronary artery disease; restenosis; chemokines; eicosanoids;

    Abstract : Atherosclerosis and restenosis are driven by chronic immune response in the vascular wall. This involves cell migration into and within the vessel wall, cell proliferation as well as accumulation of lipids in the vessel wall. These processes are mediated, among other substances, by molecules belonging to a large family of chemoattractants. READ MORE