Search for dissertations about: "Macrophages pathology"
Showing result 21 - 25 of 55 swedish dissertations containing the words Macrophages pathology.
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21. Mycobacterial infection: Immune evasion, host susceptibility and immunological markers of diagnostic importance
Abstract : IIn the first study, we investigated the functional implications of prolonged TLR signalling on IFN-γ mediated killing of mycobacteria by murine macrophages in vitro. TLR2, but not TLR4 ligation interfered with IFN-γ mediated killing of mycobacteria in macrophages. READ MORE
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22. Modulation of mononuclear phagocyte function in the dissemination of Toxoplasma gondii
Abstract : Toxoplasma gondii is an obligate intracellular Apicomplexan parasite that could possibly infect all warm-blooded animals. Acute infections with T. READ MORE
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23. Rho-GTPases in Rheumatoid Arthritis
Abstract : The success of alleviating rheumatoid arthritis (RA) symptoms is complicated by both heterogeneity of the disease and lack of predictive markers to guide treatment options. Deregulated Rho-GTPases, a family of hydrolase enzymes catalyzing guanosine triphospate (GTP) to guanosine diphospate (GDP), have a detrimental role in many diseases including RA. READ MORE
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24. Phagocytic cells and Streptococcus pyogenes in invasive infections : an inflammatory relationship
Abstract : Severe Streptococcus pyogenes infections, such as streptococcal toxic shock syndrome and necrotizing soft tissue infections, are rare but life threatening conditions. They are characterized by high bacterial load and a hyper-inflammatory state. The aim of this thesis was to investigate interactions between S. READ MORE
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25. Oral chronic Graft-versus-host disease : clinical and pathological staging
Abstract : Allogenic hematopoietic cell transplantation (HCT) is a curative treatment for many patients with immune- hematopoietic disorders, mainly hematopoietic cancers as leukaemia. Chronic Graft-versus-Host Disease (cGVHD) is a major long-term complication, associated with mortality and morbidity following allogenic HCT. READ MORE