Search for dissertations about: "Macrophages"

Showing result 1 - 5 of 653 swedish dissertations containing the word Macrophages.

  2. 1. Cancer and Inflammation Role of Macrophages and Monocytes

    University dissertation from Karlstad : Karlstads universitet

    Author : Alexander Hedbrant; Jonny Wijkander; Dick Delbro; Ann Erlandsson; Anita Sjölander; [2015]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; M1 macrophages; M2 macrophages; colon cancer; lung cancer; prostaglandin E2; Biomedical Sciences; Biomedicinsk vetenskap;

    Abstract : Macrophages are cells of the innate immune system that can be found in large quantities in cancer tumors and affect cancer progression by regulating growth and invasiveness of cancer cells. There are two main phenotypes of macrophages denoted M1 and M2. READ MORE

  4. 2. Monocytes and macrophages, with a focus of Crohn's disease

    University dissertation from Gastroenterology, Dept of Clinical Sciences, Malmö, Lund University

    Author : Susanne Thiesen; [2015]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Crohn s disease; Cystatin C; Cytokines; Intestine; Macrophages; Monocytes; Gene-expression;

    Abstract : Monocytes and macrophages are part of the body’s first line of defense, eliminating pathogens by phagocytosis or by releasing a broad array of inflammatory mediators, such as cytokines, chemokines and proteases. In humans, three subsets of monocytes are described with seemingly different functions. READ MORE

  5. 3. Signal transduction in macrophages. Intracellular pathways activated by microbial constituents

    University dissertation from Institutionen för Experimentell Medicinsk Vetenskap, Lunds Universitet

    Author : Sandra Olsson; [2006]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicin människa och djur ; Medicine human and vertebrates ; TNF; TLR; dectin-1; lipid rafts; Src; Btk; Macrophages; arachidonate;

    Abstract : Macrophages play an essential role in the defense against infection by phagocytosis and by production of inflammatory mediators. Such mediators are TNF? and eicosanoids. Many microbial agents elicit arachidonate release in macrophages that lead to the formation of eicosanoids. READ MORE

  6. 4. Molecular targets for glucocorticoids in macrophages: cytosolic phospholipase A2 and cytokine formation

    University dissertation from Center for Molecular Biomedicine, Lund University

    Author : Karin Gewert; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pharmacognosy; Pharmacological sciences; signal transduction; dexamethasone; cytosolic phospholipase A2; glucocorticoids; macrophages; protein kinase C; mitogen-activated protein kinases; TNF-alpha; IL-1beta; protein phosphatases; okadaic acid; pharmacy; toxicology; Farmakologi; farmakognosi; farmaci; toxikologi;

    Abstract : The aim of this investigation has been to study mechanisms by which glucocorticoids inhibit inflammatory processes in vitro. Type IV cytosolic 85 kDa phospholipase A2 (cPLA2) is an important modulator of inflammatory responses that is present in macrophages as well as in other cell types. READ MORE

  7. 5. Signalling to Activation of Cytosolic Phospholipase A2 and Arachidonate Release in Macrophages

    University dissertation from Department of Cell and Molecular Biology, Lund University

    Author : Gösta Hiller; [2000]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; signal transduction; dexamethasone; macrophages; phospholipase C; phosphatidylinositol 3-kinase; mitogen-activated protein kinases; cytosolic phospholipase A2; arachidonic acid; Histology; cytochemistry; histokemi; cytokemi; tissue culture; Histologi; vävnadskultur; histochemistry;

    Abstract : Eicosanoids include prostaglandins, thromboxanes and leukotrienes, which are arachidonic acid oxygenation products. These lipids make important contributions to the signs and symptoms of inflammatory diseases. READ MORE