Search for dissertations about: "Magnus Essand"

Showing result 1 - 5 of 16 swedish dissertations containing the words Magnus Essand.

  2. 1. Radioimmunotargeting of cancer cells : studies on prostatic adenocarcinoma spheroids and characterization of a novel monoclonal anti-prostate antibody

    Author : Magnus Essand; Uppsala universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP;

    Abstract : .... READ MORE

  4. 2. Studies of Enterovirus Infection and Induction of Innate Immunity in Human Pancreatic Cells

    Author : Mahesh Anagandula; Magnus Essand; Didier Hober; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 1 Diabetes; Enterovirus; Innate Immunity; Pancreas;

    Abstract : Several epidemiological and clinical studies have indicated a possible role of Enterovirus (EV) infection in type 1 diabetes (T1D) development. However, the exact casual mechanism of these viruses in T1D development is not known. READ MORE

  5. 3. Adoptive T Cell Therapy of Viral Infection and Cancer : Ex vivo Expansion of Cytomegalovirus- and Prostate Antigen-specific T Cells

    Author : Björn Carlsson; Magnus Essand; Thomas Tötterman; Malcolm Brenner; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; Immunotherapy; Adoptive T cell therapy; Dendritic cell; T cell; Tetramer; Cytomegalovirus; Transplantation; pp65; Prostate cancer; TARP; Prostate antigens; Immunologi; Immunology; Immunologi;

    Abstract : The main focus of my thesis has been to develop protocols for generating antigen-specific cytotoxic T lymphocytes (CTLs) and T helper cells (TH) for adoptive transfer to treat cytomegalovirus (CMV) disease and prostate cancer. CMV viremia is a severe complication in immunocompromised stem cell transplanted patients. READ MORE

  6. 4. TARP Promoter-Based Prostate Cancer Gene Therapy : From Development to Application

    Author : Wing-Shing Cheng; Magnus Essand; Thomas H. Tötterman; Cecilia Lundberg; Uppsala universitet; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Genetic engineering; TARP; PPT; TSTA; promoter; gene regulation; prostate specificity; hormone- independent; adenovirus; prostate cancer; gene therapy; conditionally replicating adenovirus; Genteknik; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Abstract : Prostate cancer is one leading cause of cancer-related death among men in Western countries. The standard therapies for localized prostate cancer include radical prostatectomy and radiation therapy. Such measures are relatively effective in the short term, but many patients ultimately relapse. READ MORE

  7. 5. Adenovirus-mediated CD40 Ligand Immunotherapy of Prostate and Bladder Cancer

    Author : Helena Dzojic; Magnus Essand; Thomas H Tötterman; Aristides Eliopoulos; Uppsala universitet; []
    Keywords : Medicine; immunotherapy; gene therapy; prostate cancer; bladder cancer; adenoviral vector; CD40 ligand; promoter; PPT; TSTA; depsipeptide FK228; TRAMP-C2; Medicin;

    Abstract : Cancer immunotherapy aims at reversing the immunosuppressive tumor environment and enhancing anti-tumor immunity. This thesis comprises studies on murine models for prostate (TRAMP-C2) and bladder (MB49) cancer with the aim to explore if the introduction of an adenoviral vector expressing CD40 ligand (AdCD40L) can induce anti-tumor immune responses. READ MORE