Search for dissertations about: "Major histocompatibility complex"

Showing result 16 - 20 of 122 swedish dissertations containing the words Major histocompatibility complex.

  2. 16. Heritability and sex differences in experimental neuropathic pain with special emphasis on the role of the major histocompatibility complex

    Author : Cecilia Dominguez; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Neuropathic pain caused by injury to the nervous system is a difficult clinical problem and a large proportion of patients experience no or only partial relief from existing treatments. Pain sensitivity and the development of neuropathic pain are complex biological and physiological entities that are known to be affected by genetics and sex. READ MORE

  4. 17. Dendritic cell interactions with Gram negative bacteria

    Author : Mattias Svensson; Immunologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mycology; virology; Major histocompatibility complex molecules; Dendritic cells; Gram negative bacteria; Antigen processing; Antigen presentation; bacteriology; Microbiology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Abstract : The interaction between murine bone marrow-derived dendritic cells (DC) and the Gram negative bacteria Salmonella typhimurium and Escherichia coli have been characterised. These studies showed that DC phagocytosed and processed S. typhimurium and E. READ MORE

  5. 18. Evolution of MHC Genes and MHC Gene Expression

    Author : Karin Berggren Bremdal; Hans Ellegren; Jennifer Seddon; Philip Hedrick; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; major histocompatibilty complex; dog leukocyte antigen; balancing selection; linkage disequilibrium; promoter; diabetes mellitus; Canis familiaris; Canis lupus; Erinaceus europaeus; Erinaceus concolor; Genetics; Genetik; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Abstract : Polymorphism in coding regions and regions controlling gene expression is the major determinant of adaptive differences in natural populations. Genes of the major histocompatibility complex (MHC) possess a high level of genetic variation, which is maintained by selection over long coalescence times. READ MORE

  6. 19. MHC class I - Peptide binding and complex stability

    Author : Elna Follin; Antigen presentation; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The major histocompatibility class I (MHC-I) genes are highly polymorphic and the proteins that they encode play a crucial role in both the innate and the adaptive immune response. A MHC-I molecule consists of three parts, one polymorphic heavy chain, one invariant light chain, β2-microglobulin and a peptide of usually between 8-11 amino acids in length. READ MORE

  7. 20. Immunoecology of the Great Snipe (Gallinago media) : Mate Choice, MHC Variation, and Humoral Immunocompetence in a Lekking Bird

    Author : Robert Ekblom; Jacob Höglund; Mats Grahn; Scott V. Edwards; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Biology; Behaviour; Major histocompatibility complex class II B; Sexual selection; Evolution; Leks; Biologi; Biology; Biologi;

    Abstract : At the centre of the vertebrate immune system is a group of proteins called MHC (major histocompatibility complex) molecules. These function in self – non self recognition and activation of the immune defence against intruding parasites and pathogens. READ MORE