Search for dissertations about: "Major histocompatibility complex"

Showing result 21 - 25 of 122 swedish dissertations containing the words Major histocompatibility complex.

  2. 21. Analysis of genetic susceptibility to cervical cancer using candidate gene and GWAS approaches

    Author : Ivana Juko-Pecirep; Ulf Gyllensten; Holger Luthman; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cervical cancer; association study; human papillomavirus; genetics; complex disease; TMC6; TMC8; MHC region; Medical Genetics; Medicinsk genetik;

    Abstract : Cervical cancer is the forth most commonly diagnosed cancer among women worldwide. It is caused by persistent infection with an oncogenic type of Human Papillomavirus (HPV). The HPV is a necessary but not sufficient cause of cervical cancer. READ MORE

  4. 22. Genetic regulation of, and autoimmunity in, myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis and multiple sclerosis

    Author : Erik Wallström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : multiple sclerosis; experimental autoimmune encephalomyelitis; myelin oligodendrocyte glycoprotein; autoimmunity; major histocompatibility complex;

    Abstract : Multiple sclerosis (MS) is a chronic disease of the central nervous system (CNS) with inflammation and plaques of demyelination. This thesis examines the genetic and immunological requirements or rat experiment autoimmune encephalomyelitis (EAE), an animal model of MS, to display both inflammatory and demyelinated CNS lesions with chronic and/or relapsing-remitting disease courses. READ MORE

  5. 23. Characterisation of psoriasis lesions by protein expression profiling

    Author : Lina Carlén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Complex disease; psoriasis; proteomics; human leukocyte antigen C HLA-C ; major histocompatibility complex; 2D PAGE; inflammation; skin disease;

    Abstract : Psoriasis is a common inflammatory skin disease affecting approximately 2% of the population in Sweden. Psoriasis displays clinical heterogeneity leading to several different types of manifestations, among them chronic plaque and acute guttate psoriasis, the two most common forms of the disease. READ MORE

  6. 24. Study of the psoriasis proteome and analysis of MHC class I expression and function

    Author : Lina Carlén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Complex disease; psoriasis; proteomics; human leukocyte antigen C HLA-C ; major histocompatibility complex; 2D PAGE; inflammation; skin disease;

    Abstract : Psoriasis is a common inflammatory skin disease affecting approximately 2% of the population in Sweden. Psoriasis displays clinical heterogeneity leading to several different types of manifestations, among them chronic plaque and acute guttate psoriasis. READ MORE

  7. 25. Immunogenetics and treatment of experimental autoimmune encephalomyelitis

    Author : Robert Weissert; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Multiple sclerosis; experimental autoimmune encephalomyelitis; major histocompatibility complex; myelin; myelin oligodendrocyte glycoprotein; T cell receptor;

    Abstract : Experimental autoimmune encephalomyelities (EAE) is a model of multiple sclerosis (MS). This experimental central nervous system (CNS) disease can be induced in rats by immunization with components of the CNS myelin sheath. READ MORE