Search for dissertations about: "Majority Populations"
Showing result 21 - 25 of 187 swedish dissertations containing the words Majority Populations.
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21. Statistical methods for the detection and analyses of structural variants in the human genome
Abstract : Structural variations (SVs) are an important and abundant source of variation in the human genome, encompassing a greater proportion of the genome as compared to single nucleotide polymorphisms (SNPs). This thesis investigates different aspects of SV analysis, focusing on copy number variations (CNVs) and regions of homozygosity (ROHs). READ MORE
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22. New aspects of tissue mast cells in inflammatory airway diseases
Abstract : Mast cell are found throughout the body, but are especially prominent in tissues that have direct contact with the external milieu such as the skin, gastrointestinal tract and lungs. Mast cells are commonly recognized for their detrimental role in allergic reactions and can, upon activation through the high-affinity receptor for IgE (FcεRI), rapidly produce and secrete many of the mediators responsible for the typical symptoms in urticaria, asthma and rhinitis. READ MORE
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23. Population fluctuations and life history consequences in the arctic fox
Abstract : In this thesis, I describe and explain drastic population fluctuations in the arctic fox Alopex lagopus (L.). I proceed to examine evolutionary consequences of unpredictable fluctuations in terms of life history strategies. In fluctuating populations, the risks and benefits of different behaviours vary with changes in population density. READ MORE
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24. Thermal components in the early X-ray afterglow of gamma-ray bursts
Abstract : Gamma-ray bursts (GRBs) are still puzzling scientists even 40 years after their discovery. Questions concerning the nature of the progenitors, the connection with supernovae and the origin of the high-energy emission are still lacking clear answers. Today, it is known that there are two populations of GRBs: short and long. READ MORE
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25. Experimental studies on multidrug resistance in human leukaemia : role of cellular heterogeneity for daunorubicin kinetics
Abstract : Cellular resistance to chemotherapy is a major cause of treatment failure in acute myeloid leukaemia (AML) and still the majority of the patients die from their disease. Drug resistance 1s multifactorial, the most studied mechanism being multidrug resistance (MDR), mediated by the P-glycoprotein (Pgp). READ MORE