Search for dissertations about: "Malaria susceptibility"
Showing result 1 - 5 of 29 swedish dissertations containing the words Malaria susceptibility.
-
1. Genetic analysis of murine malaria
Abstract : Malaria, an infectious disease caused by Plasmodium parasites, is one of the major world-scale health problems. Despite the efforts aimed at finding an effective way to control the disease, the success has been thwarted by the emergence of parasite drug resistance and mosquito resistance to insecticides. READ MORE
-
2. Antibody responses and Fc gamma receptor IIa polymorphism in relation to Plasmodium falciparum malaria
Abstract : Immunity to asexual blood-stage of Plasmodium falciparum malaria is believed to be associated with protective antibodies of certain immunoglobulin classes and subclasses. This thesis addressed the importance of antibodies in relation to malaria infection and their effective interactions with Fc gamma receptor IIa (FcyRIIa) polymorphisms. READ MORE
-
3. Dissecting the complexity of human susceptibility to Plasmodium falciparum malaria: genetic approaches
Abstract : There are many aspects of the immunology of P. falciparum infection that are not understood. Genetic approaches are of great value for dissecting the complexity of immune responses to malaria in natura by providing new insights into molecular interactions between the parasite and the host. READ MORE
-
4. Studies of Thai blood group and platelet polymorphism. Implications for malaria susceptibility
Abstract : The objectives of the thesis were to seek a better understanding of polymorphic RBC surface molecules in the Thai, and to investigate the role of certain blood groups in malarial invasion. MALDI-TOF MS was employed in Study I as an efficient method for genotyping to establish the common blood group and platelet antigen genotypes of 396 blood donors. READ MORE
-
5. T cell and antibody responses in Plasmodium falciparum malaria and their relation to disease susceptibility
Abstract : Malaria antigen-induced polarization of T cells into effectors Th1 and/or Th2 cells and their subsequent release of cytokines is known to affect antibody production. This thesis includes studies on early innate responses to the parasite, with a focus on γδT cells, and acquired specific responses in African sympatric ethnic tribes. READ MORE