Search for dissertations about: "Malaria"

Showing result 11 - 15 of 275 swedish dissertations containing the word Malaria.

  1. 11. Vaccine development strategies applied to the Plasmodium falciparum malaria antigen 332

    Author : Nina-Maria Vasconcelos; Klavs Berzins; Matti Sällberg; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; malaria; sub-unit vaccines; immunogenicity; antibody response; antigen Pf332; Immunology; Immunologi;

    Abstract : Malaria is one of the major infectious diseases in the world with regard to mortality and morbidity, and the development of a vaccine against the malaria parasite Plasmodium falciparum is considered of high priority. The aim of the work presented in this thesis was to develop and characterize recombinant vaccine constructs based on the P. READ MORE

  2. 12. Structure-Assisted Design of Drugs Towards HIV-1 and Malaria Targets : Applied on Reverse Transcriptase and Protease from HIV-1 and Plasmepsin II from Plasmodium falciparum

    Author : Jimmy Lindberg; Torsten Unge; Alexander Wlodawer; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; X-ray crystallography; Drug design; HIV-1; Malaria; Molekylärbiologi; Molecular biology; Molekylärbiologi;

    Abstract : Globally of today, acquired immunodeficiency syndrome (AIDS) and malaria are two of the most threatening diseases known to mankind. The World Health Organization estimated that AIDS and malaria together claimed nearly 4 million lives in 2003 and many more were infected by the causative agent human immunodeficiency virus (HIV) and the Plasmodium falciparum (P. READ MORE

  3. 13. Oviposition cues as a tool for developing a new malaria control strategy

    Author : Lynda Eneh; Anna-Karin Borg-Karlson; Willem Takken; KTH; []
    Keywords : Anopheles gambiae; Malaria; Oviposition; Volatile compounds; GC-MS; DGGE; Sorption; Fungi; Bacteria; Physicochemical parameters; Nut grass; Bermuda grass; Anopheles gambiae; Malaria; Äggläggning; Flyktiga ämnen; GC-MS; DGGE; Sorptionen; Svampar; Bakterier; Gräs; Kemi; Chemistry;

    Abstract : Anopheles gambiae sensu lato mosquitoes are among the dominant malaria vectors in sub-Saharan Africa. However, not much is known about the oviposition behaviour of these species necessary for the development of malaria vector control strategies. READ MORE

  4. 14. Dissecting the complexity of human susceptibility to Plasmodium falciparum malaria: genetic approaches

    Author : Valentina D Mangano; Marita Troye-Blomberg; Marta Alarcon; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; immunology; genetics; malaria; Immunology; Immunologi; immunologi; Immunology;

    Abstract : There are many aspects of the immunology of P. falciparum infection that are not understood. Genetic approaches are of great value for dissecting the complexity of immune responses to malaria in natura by providing new insights into molecular interactions between the parasite and the host. READ MORE

  5. 15. Identification of bacteria associated with malaria mosquitoes - Their characterisation and potential use

    Author : Jenny Lindh; Ingrid Faye; Marcelo Jacobs-Lorena; Stockholms universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Malaria; mosquito; Anopheles; bacteria; paratransgenics; semiochemicals; Molecular biology; Molekylärbiologi; molekylärgenetik; Molecular Genetics;

    Abstract : The use of transformed bacteria to stop or kill disease-causing agents in the gut of vector insects is called paratransgenics. Two of the major steps in creating a paratransgenic Anopheles mosquito, unable to spread the Plasmodium parasites that cause malaria, are to find a bacterium suitable for the purpose and a way to introduce the transformed bacterium into mosquitoes in the field. READ MORE