Search for dissertations about: "Malarone"
Found 4 swedish dissertations containing the word Malarone.
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1. Pharmacokinetics and dynamics of atovaquone and proguanil (Malarone®)
Abstract : Malarone® is a fixed dose combination of atovaquone and proguanil and is mainly used for prophylaxis against P. falciparum malaria as an alternative to Lariamo® or chloroquine+proguanil. READ MORE
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2. Development of Analytical Methods for Measurement of Drugs against Malaria in Plasma and Whole Blood
Abstract : The aim of this thesis was to develop analytical methods for measuring drugs in blood and/or plasma. Solid phase extraction was used for the enrichment and purification of the drugs from the sample matrix. READ MORE
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3. Experimental pharmacodynamic and kinetic studies related to new combination therapies against P. falciparum malaria
Abstract : Artemisinin (ART) class of compounds are of special interest due to their rapid onset of action and high activity against multidrug resistant malaria. The major drawback in monotherapy with ART and its derivatives is the high rate of recrudescent infection. READ MORE
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4. Development of Field-adapted Analytical Methods for the Determination of New Antimalarial Drugs in Biological Fluids
Abstract : This thesis deals with the development of analytical methods for the determination of new antimalarial drugs in biological fluids. The goal was to develop methods that facilitate clinical studies performed in the field, such as capillary blood sampling onto sampling paper. READ MORE