Search for dissertations about: "Malgorzata Pokrzywa"

Found 1 swedish dissertation containing the words Malgorzata Pokrzywa.

  2. 1. A Drosophila Disease-Model for Transthyretin-associated Amyloidosis

    Author : Malgorzata Pokrzywa; Erik Lundgren; Damian Crowther; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; transthyretin; amyloid; amyloidosis; Drosophila; transthyretin-associated amyloidosis; Familial amyloid polyneuropathy; neurodegeneration; serum amyloid P component; Non-steroidal Anti-Inflammatory Drugs; drug screens; Molecular biology; Molekylärbiologi;

    Abstract : Amyloidoses comprise a group of gain-of-toxic function protein misfolding diseases, in which normally soluble proteins in their functional state undergo conformational changes into highly organized and generally intractable thread-like aggregates, termed amyloid fibrils. These structures accumulate predominantly in the extracellular space but growing evidence suggests that amyloids may start to form intracellularly. READ MORE