Search for dissertations about: "Malignant salivary"

Showing result 1 - 5 of 9 swedish dissertations containing the words Malignant salivary.

2. 1. Head and Neck Cancer : Factors Affecting Tumour Growth

   Author : Kaarina Sundelin; Elisabeth Paulette-Hultcrantz; Karin Öllinger; Karin Roberg; Hans Gustafsson; Linköpings universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Head and neck cancer; Chemoradiotherapy; Tumour; Malignant salivary; Metallothionein; Neo-angiogenesis; Metastases; Cytokine tumour necrosis factor-alpha; hepatocyte growth factor; Oncology; Onkologi;

   Abstract : Head and neck cancer is the fifth most common cancer worldwide with an estimated annual global incidence of over 500 000 cases. These malignant tumours develop in the mucosal linings of the upper respiratory tract or in the salivary glands. The most common sites are in the oral cavity and larynx. READ MORE

4. 2. Studies of gene fusions and copy number alterations in salivary and adnexal neoplasms

   Author : Marta Persson; Göteborgs universitet; []
   Keywords : cancer genetics; fusion oncogenes; chromosome translocation; MYB; NFIB; CRTC1; MAML2; salivary gland; breast; adenoid cystic carcinoma; mucoepidermoid carcinoma; hidradenoma;

   Abstract : Cancer is a genetic disease caused by the accumulation of genetic changes such as mutations and chromosomal rearrangements. An increasing number of genetic studies of both hematological and solid neoplasms have shown that recurrent chromosome translocations often result in fusion oncogenes. READ MORE

5. 3. Salivary function after pediatric bone marrow transplantation

   Author : Mats Bågesund; Karolinska Institutet; Karolinska Institutet; []
   Keywords : bone marrow transplantation; total body irradiation; cancer; children; saliva; xerostomia; scintigraphy;

   Abstract : Salivary gland dysfunction is one of the oral long-term complications that most affect the quality of life among long-term survivors after treatment for malignant diseases. The aims of the studies in this thesis were to examine the effect of pediatric bone marrow transplantation (BMT) conditioning regimens on salivary function, caries-associated microflora, and development of dental caries; define risk factors of salivary dysfunction; evaluate subjective xerostomia; and study functional disturbances in the major salivary glands using salivary gland scintigraphy (SGS). READ MORE

6. 4. Transcriptomic and functional studies of fusion oncogene-driven salivary gland tumors

   Author : Maryam K. Afshari; Göteborgs universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; fusion oncogene; MYB; NFIB; PLAG1; HMGA2; adenoid cystic carcinoma; pleomorphic adenoma; targeted therapy;

   Abstract : Fusion genes are potent oncogenic drivers resulting from exchange of regulatory/coding sequences between two genes. They were originally identified in leukemias but are now recognized as key oncogenic events also in many solid tumors, including salivary gland tumors (SGTs). READ MORE

7. 5. Radiolabeled acetate PET in oncology imaging : studies on head and neck cancer, prostate cancer and normal distribution

   Author : Aijun Sun; Jens Sörensen; Silvia Johansson; Mikael Karlsson; Katrine Åhlström Riklund; Ingela Turesson; Heikki Minn; Umeå universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; 11C-acetate; 18F-fluoroacetate; PET; head and neck cancer; staging; delineating tumor volume; clearance rate; perfusion; RT; treatment outcome; benign and malignant lymph node; prostate cancer; normal distribution; Oncology; Onkologi; onkologi; Oncology;

   Abstract : The use of positron emission tomography (PET) for imaging in oncology has grown rapidly in recent years. 2-[18F]-fluorodeoxyglucose (FDG) is the most common tracer of PET, although drawbacks exist. READ MORE