Search for dissertations about: "Malignant"

Showing result 21 - 25 of 1031 swedish dissertations containing the word Malignant.

  2. 21. Isolated regional perfusion for metastases of malignant melanoma - Clinical and experimental studies

    Author : Roger Olofsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malignant melanoma; Uveal melanoma; Isolated limb perfusion; Isolated hepatic perfusion; Immunology; Exosomes;

    Abstract : Background: Isolated regional perfusion is a treatment option mainly for localized metastatic disease. The principle idea is to surgically isolate a region of the body and connect the circulation to a heart-lung machine. A high concentration of a chemotherapeutic agent is then delivered to the tumour, while systemic toxicity is avoided. READ MORE

  4. 22. Immunotherapy and COX-2 inhibition against malignant brain tumors

    Author : Sofia Eberstål; Neurokirurgi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Malignant brain tumors; immunotherapy; IFN-γ; GM-CSF; COX-2 inhibition;

    Abstract : Glioblastoma multiforme (GBM) is the most common primary brain tumor in the central nervous system and the prognosis is very poor despite conventional therapies including surgery, chemo- and radiotherapy. Peripheral vaccination with irradiated tumor cells represent a novel therapy that targets both dividing and non-dividing tumor cells and minimizes the risk of therapy resistance by presenting multiple tumor antigens. READ MORE

  5. 23. Malignant melanoma in children and adolescents

    Author : Peter Berg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Melanoma; epidemiology; cancer register; children; adolescents; incidence; phototherapy; hyperbilirubinaemia; etiological factors; congenital nevi; heredity; CDKN2A; germline mutation.;

    Abstract : The aim of the work reported in the present thesis was to investigate malignant melanoma in children and adolescents. Through epidemiological studies, we wished to investigate incidence, clinical factors and prognosis and to study the records. READ MORE

  6. 24. Early effects of castration therapy in non-malignant and malignant prostate tissue

    Author : Nina Ohlson; Pernilla Wikström; Anders Bergh; Pär Stattin; Marja Nevalainen; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; human biopsies; androgen ablation; stroma; epithelium; micro-dissection; PSA; IGF-1; IGF-R1; AR; Pathology; Patologi;

    Abstract : Early Effects of Castration Therapy in Non-malignant and Malignant Prostate Tissue BACKGROUND. Androgen ablation, the standard treatment for advanced prostate cancer, results in increased apoptosis, decreased cell proliferation and subsequent involution of the prostate gland. READ MORE

  7. 25. Molecular genetics of cutaneous malignant melanoma

    Author : Malihe Eskandarpour; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cutaneous malignant melanoma is an aggressive tumor of melanocytes in the skin with rapidly increasing incidence. Patients with advanced disease have a poor prognosis since the tumor is usually resistant to current therapies. Therefore, the development of novel strategies for preventing and treating melanoma is important. READ MORE