Search for dissertations about: "Malin Celander"

Found 3 swedish dissertations containing the words Malin Celander.

  2. 1. Experimental Studies of Endocrine Disrupting Compounds in Vascular Cells and Tissues

    Author : Helén Andersson; Eva Brittebo; Malin Celander; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrine disrupting compounds; endothelium; vascular toxicity; Toxicology; Toxikologi;

    Abstract : Epidemiological evidence suggest that exposure to endocrine disrupting compounds (EDCs) is a risk factor for diseases that involves the cardiovascular system but we know little about the mechanisms whereby these compounds can cause injury in the vasculature. The aim of this thesis was to characterize the effects and mechanisms of some EDCs in vascular cells and highly vascularized tissues. READ MORE

  4. 2. The impact of cytochrome P4501-inhibitors on aryl hydrocarbon receptor signaling

    Author : Johanna Bengtsson; Emma Wincent; Ulf Rannug; Malin Celander; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molekylär biovetenskap; Molecular Bioscience;

    Abstract : The aryl hydrocarbon receptor (AHR) best known as a ligand-activated transcription factor that mediates toxic responses to xenobiotics such as dioxins, is also activated by certain endogenous compounds. Activation of the AHR up-regulates transcription of a large number of genes, including those encoding members of the cytochrome P450 1 family of enzymes (CYP1s). READ MORE

  5. 3. Molecular and phenotypical toxicological effects of environmental pollutants and their mixtures : A mechanistic approach

    Author : Greta Nilén; Steffen Keiter; Maria Larsson; Nikolai Scherbak; Magnus Engwall; Malin Celander; Örebro universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Environmental pollutants; mixtures; soil; zebrafish; Danio rerio; behavior; gene expression; lipidomics; image analysis; PCB126; PFOS; B[a]P; Arsenic; risk assessment;

    Abstract : Current environmental risk assessment of polluted sites primarily relies on single compound evaluation. However, in the environment, organisms are often exposed to complex mixtures of pollutants. READ MORE