Search for dissertations about: "Malin Jarvius"
Found 3 swedish dissertations containing the words Malin Jarvius.
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1. Visualization of Protein Activity Status in situ Using Proximity Ligation Assays
Abstract : In 2001 the human proteome organization (HUPO) was created with the ambition to identify and characterize all proteins encoded in the human genome according to several criteria; their expression levels in different tissues and under different conditions; the sub-cellular localization; post-translational modifications; interactions, and if possible also the relationship between their structure and function.When the knowledge of different proteins and their potential interactions increases, so does the need for methods able to unravel the nature of molecular processes in cells and organized tissues, and ultimately for clinical use in samples obtained from patients. READ MORE
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2. Quiescent cancer cells : Three-dimensional cell models for evaluation of new therapeutics
Abstract : Inadequate metabolic conditions in solid tumors lead to the formation of quiescent cancer cells that are suspended in a transient cell cycle arrest. When conditions change, quiescent cancer cells can re-enter the cell cycle and cause recurrence. READ MORE
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3. Preclinical tumor-immune modeling : For the identification of immunomodulatory drugs
Abstract : For a long time, the field of cancer research was dominated by a tumor cell-centric view. That, however, changed once it became recognized that medical cancer treatment is largely influenced by the combined effect exerted on both cancer and immune cells. READ MORE
