Search for dissertations about: "Malmö Klinisk koagulationsmedicin"

Showing result 1 - 5 of 17 swedish dissertations containing the words Malmö Klinisk koagulationsmedicin.

  1. 1. Register-based studies to assess long-term outcome in haemophilia

    Author : Mehdi Osooli; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Registers; Haemophilia; Carriers of haemophilia; Long-term outcomes; Joint surgery; Survival; Longitudinal Studies;

    Abstract : IntroductionHaemophilia is a X-linked bleeding disorder affecting mostly males. Women are mainly carriers ofhaemophilia, however, they can expereince high bleeding tendency and assocaited symptoms aswith males. In the absence of the appropriate treatment, bleedings, especially into the joints, result inadverse outcomes. READ MORE

  2. 2. Co-morbidity and mortality in Swedish patients with haemophilia - A register study

    Author : Susanna Lövdahl; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haemophilia; registry; HIV; viral hepatitis; malignancy; hypertension; cardiovascular disease;

    Abstract : Haemophilia is an X-linked inherited recessive disorder affecting males. The increased risk of hemorrhage is explained by the deficiency in either coagulation factor VIII (haemophilia A) or IX (haemophilia B). The severity of haemophilia A and B is characterized by the bleeding pattern. READ MORE

  3. 3. Clinical probability assessment and biochemical markers in the diagnosis of deep vein thrombosis

    Author : Johan Elf; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Venous thrombosis; APC-PCI complex.; D-Dimer; Clinical probability; Diagnosis;

    Abstract : The combination of pre-test clinical probability assessment and D-dimer test is now widely applied in the diagnostic process of DVT. The general objective of the present investigation was to validate these results in a Swedish routine emergency setting were the prevalence of the disease is high and were the clinical probability assessment was handled by many junior physicians. READ MORE

  4. 4. Haemophilia A - In pursuit of optimised outcomes via personalised treatment

    Author : Alexandros Arvanitakis; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : Haemophilia A (HA) is a hereditary bleeding disorder, characterised by deficiency of coagulation factor VIII (FVIII). Repeated joint bleeds can lead to permanent joint damage. FVIII replacement therapy has a high cost and can reduce but not completely prevent bleeding. READ MORE

  5. 5. Pharmacokinetic dosing of factor VIII and factor IX in prophylactic treatment of haemophilia

    Author : Maj Carlsson; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematology; Prophylaxis; Pharmacokinetics; Pharmaceutical service; Haemophilia B; Haemophilia A; Factor IX; Factor VIII; Drug distribution; Cost-effectiveness; Dosage; extracellular fluids; Hematologi; extracellulära vätskor;

    Abstract : The aim of the thesis was to increase cost-effectiveness in prophylactic treatment of haemophilia. Prophylaxis is effective to prevent bleedings and arthropathy, but the high cost limits its use. First, a new distribution system for clotting factor concentrates was implemented in Sweden to improve availability and reduce risks and costs. READ MORE