Search for dissertations about: "Malmö Klinisk koagulationsmedicin"

Showing result 6 - 10 of 17 swedish dissertations containing the words Malmö Klinisk koagulationsmedicin.

  2. 6. Resistance to activated protein C a novel risk factor for venous thrombosis

    Author : Peter Svensson; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; APC resistance; mutation; venous thrombosis; blood coagulation; Protein C; factor V; Haematology; extracellular fluids; Hematologi; extracellulära vätskor;

    Abstract : Activated protein C resistance (APC resistance) is the most common hereditary condition associated with venous thrombosis. The syndrome known as APC resistance is perfectly linked to a mutation in the gene coding coagulation FV (FV:Q506) mutation changing Arg 506 to Gln in the APC cleavage site. READ MORE

  4. 7. Exploring Anti-FVIII Antibodies in Haemophilia A - Role in In Vitro Haemostasis and Clinical Disease

    Author : Jenny Klintman; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hemophilia A; inhibitors; non-neutralizing anti-FVIII antibodies; thrombin generation assay; ELISA;

    Abstract : Haemophilia A (HA) is caused by defective synthesis of coagulation factor VIII(FVIII), which has serious effects on haemostasis; joints being the most common site of bleeding. The development of FVIII replacements has improved the situation for patients with haemophilia such that chronic arthropathy can be prevented, and life expectancy and the quality of life have increased. READ MORE

  5. 8. Genetic Screening in Patients Suspected of Inherited Bleeding Disorders

    Author : Marcus Fager Ferrari; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bleeding; Inherited Bleeding Disorders; Platelet Dysfunction; Thrombocytopenia; Genetic Screening; High-Throughput Sequencing; STX11; STXBP2; UNC13D; FGB; COL1A1; COL3A1; COL5A1; COL5A2; GNE; Sialic Acid; Oseltamivir;

    Abstract : Inherited bleeding disorders constitute a heterogeneous group of genetic diseases, affecting virtually all major components of the hemostatic system. The diagnostics are potentially complex, and a high proportion of patients remain without a conclusive diagnosis following work-up. READ MORE

  6. 9. Bone Mineral Density in Haemophilila: A Treatment Outcome

    Author : Mohammed Khawaji; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haemophilia; Bone mineral density; Prophylaxis; Health related quality of life; Physical activity.;

    Abstract : Background: Osteoporosis is increasingly recognised as one of the major public health problems throughout the world and has massive socioeconomic implications. It has previously been shown that patients with severe haemophilia and not receiving any prophylactic treatment render a high risk of reduced bone density. READ MORE

  7. 10. Genetic characterization of families with von Willebrand disease

    Author : Elsa Lanke; Malmö Klinisk koagulationsmedicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mutation; bleeding; coagulation; von Willebrand disease; genetics;

    Abstract : von Willebrand disease (VWD) is the most common hereditary bleeding disorder. It is caused by quantitative and/or qualitative defects of the von Willebrand factor (VWF). The severity of the disease can vary considerably, as can the hereditary patterns. READ MORE