Search for dissertations about: "Malou Friederich"

Found 2 swedish dissertations containing the words Malou Friederich.

  2. 1. The Role of Mitochondrial Uncoupling in the Development of Diabetic Nephropathy

    Author : Malou Friederich Persson; Fredrik Palm; Richard K. Porter; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Kidney; mitochondria; Uncoupling Protein-2; Adenosine Nucleotide Transporter; uncoupling; diabetes; diabetic nephropathy; db db; dinitrophenol; Coenzyme Q10; oxygen; rats; mice; Physiology; Fysiologi; Medical Cell Biology; Medicinsk cellbiologi;

    Abstract : Diabetes is closely associated with increased oxidative stress, especially originating from the mitochondria. A mechanism to reduce increased mitochondria superoxide production is to reduce the mitochondria membrane potential by releasing protons across the mitochondria membrane. READ MORE

  4. 2. The Role of Kidney Oxygen Homeostasis for the Development of Kidney Disease

    Author : Carla Carvalho; Fredrik Palm; Peter Hansell; Malou Friederich; Jenny Nyström; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oxygen; Kidney mitochondria; Hypoxia-inducible factors; Prolyl hydroxylase; von Hippel-Lindau; Diabetes; Aging; Kidney; Sodium; RAAS; Fysiologi; Physiology;

    Abstract : The relation between oxygen supply and demand determines tissue oxygen tension (PO2). When intrarenal tissue PO2 decreases, any compensatory increase in oxygen supply via increased renal blood flow is likely to increase glomerular filtration rate. READ MORE