Search for dissertations about: "Marcel René Bouw"
Found 1 swedish dissertation containing the words Marcel René Bouw.
1. Microdialysis as a tool in pharmacokinetic-pharmacodynamic studies investigating the brain distribution and effect delay of morphine and morphine-6-glucuronideUniversity dissertation from Uppsala : Acta Universitatis Upsaliensis
Abstract : The microdialysis technique was developed as a tool for studying the pharmacokinetic and pharmacodynamicrelationships of morphine and morphine-6-glucronide (M6G). Concentrations of unbound drug in blood andbrain were monitored in order to elucidate the origin of the observed delay in antinociceptive effect in rats. READ MORE